Sistema de Salut de Catalunya
[Marín Soro M] Institute of Neuroscience, Autonomous University of Barcelona, Spain. [Gisbert Gustemps L] Hospital Vall d'Hebron, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Boix Alonso H] Quirón Hospital, Barcelona, Spain. [Martínez-Maldonado S] Universitat Oberta de Catalunya, Barcelona, Spain. [Coronado Contreras R] General Hospital of Granollers, Granollers, Spain. Hospital Universitari Mollet, Fundació Sanitaria Mollet, Mollet del Vallès, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain
Hospital General de Granollers
2026-02-12T11:41:11Z
2026-02-12T11:41:11Z
2024-11
Trastorno del espectro autista; Diagnóstico temprano; Bajo peso al nacer
Autism spectrum disorder; Early diagnosis; Low birth weight
Trastorn de l'espectre autista; Diagnòstic precoç; Baix pes en néixer
Introduction: Very preterm birth is an important risk factor for autism spectrum disorder (ASD). The aim of this study is the early detection of ASD risk, using a follow-up protocol, in children weighing less than 1500 g at birth or born before 32 weeks of gestation. Methods: This is a prospective longitudinal study in which a total of 133 very premature babies were monitored to the age of 2 years with the M-CHAT autism screening test and, in the event of a positive result, the Autism Diagnostic Observation Schedule (ADOS-2). Results: 53 cases (4 out of 10) screened positive, and the rest negative. Among the positives, the ADOS-2 was administered in 50 cases, of which 24 scored above the ASD cutoff point. The average age of detection was 25.39 months. The results suggest an estimated prevalence of ASD in the very premature population of 18.46 %. Conclusions: The application of the follow-up protocol in the very premature population is effective for early detection of ASD.
Article
Published version
English
Diagnòstic; Part prematur; Autisme - Factors de risc; PSYCHIATRY AND PSYCHOLOGY::Mental Disorders::Neurodevelopmental Disorders::Child Development Disorders, Pervasive::Autism Spectrum Disorder; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors; DISEASES::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Obstetric Labor Complications::Obstetric Labor, Premature::Premature Birth; PSIQUIATRÍA Y PSICOLOGÍA::trastornos mentales::trastornos del desarrollo neurológico::trastornos generalizados del desarrollo del niño::trastorno del espectro del autismo; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo; ENFERMEDADES::enfermedades de los genitales femeninos y complicaciones del embarazo::complicaciones del embarazo::complicaciones del parto::parto prematuro::nacimiento prematuro
Elsevier
Brain and development;46(10)
https://doi.org/10.1016/j.braindev.2024.08.006
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
Articles científics - HG [170]
