Sistema de Salut de Catalunya
[Perez-Prieto D, Fontanellas-Fes A] Servei de Cirurgia Ortopèdica, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain. [Koetter K] Department of Health Economics & Outcome Research, Heraeus Medical GmbH, Wehrheim, Germany. [Martínez-Cruz O] Programa d’Analítica de Dades per a la Recerca i la Innovació en Salut (PADRIS), Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS), Departament de Salut, Generalitat de Catalunya, Barcelona, Spain
Departament de Salut
2025-07-03T12:02:15Z
2025-07-03T12:02:15Z
2025-05-26
Total knee arthroplasty; Bone cement; Catalan Arthroplasty Register (RACat)
Artroplàstia total de genoll; Ciment ossi; Cirurgia de revisió
Artroplastia total de rodilla; Cemento óseo; Cirugía de revisión
Clinical data on individual bone cement brands and viscosities in cemented total knee arthroplasty (TKA) is scarce. The Catalan arthroplasty registry (RACat) documents usage of cement brands including viscosities and the inclusion of antibiotics. The objective was to compare the clinical performance of the widely used bone cement brand PALACOS® to other blinded bone cement brands in TKA using data from the RACat. Patient data on 50,545 primary TKA between 2007 and 2017 in the RACat were analysed retrospectively. Implant survival of PALACOS bone cement was compared to other blinded bone cement brand groups using the all-cause revision risk as primary study endpoint. Comparing implant survival, it was found that (1) PALACOS® (with or without gentamicin) was associated with a significantly lower revision risk compared to other cement brands (with or without antibiotics) ( Type of cement brand, viscosity and the addition of antibiotics have an impact on revision risk of TKA. Medium viscosity cement with gentamicin (PALACOS MV+G), for which no clinical data were previously available, was associated with the lowest revision risk in TKA. Level III, retrospective comparative study.
Article
Published version
English
Artroplàstia total de genoll; Pròtesis; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Orthopedic Procedures::Arthroplasty::Arthroplasty, Replacement::Arthroplasty, Replacement, Knee; CHEMICALS AND DRUGS::Macromolecular Substances::Polymers::Plastics::Resins, Synthetic::Bone Cements; DISEASES::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Postoperative Complications::Prosthesis Failure; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos ortopédicos::artroplastia::artroplastia de sustitución::artroplastia de sustitución de rodilla; COMPUESTOS QUÍMICOS Y DROGAS::sustancias macromoleculares::polímeros::plásticos::resinas sintéticas::cementos óseos; ENFERMEDADES::afecciones patológicas, signos y síntomas::procesos patológicos::complicaciones posoperatorias::fallo de prótesis
Wiley
Journal of Evidence-Based Orthopaedics;12(2)
https://www.doi.org/10.1002/jeo2.70271
Attribution-NonCommercial 4.0 International
https://creativecommons.org/licenses/by/4.0/
