Sistema de Salut de Catalunya
[Oliveras, L] Servei de Nefrologia, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Spain. Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Hospital Duran i Reynals, L’Hospitalet de Llobregat, Spain. Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain. [Pareja L] Registre de Tumors Hospitalaris, Institut Català d’Oncologia (ICO), L’Hospitalet de Llobregat, Spain. Departament d’infermeria de Salut Pública, Salut Mental i Maternoinfantil, Facultat d’Infermeria, Universitat de Barcelona (UB), Barcelona, Spain. [Ribes J] Registre de Tumors Hospitalaris, Institut Català d’Oncologia (ICO), Hospitalet de Llobregat, Spain. Pla Contra el Càncer de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. Departament de Ciències Clíniques, Universitat de Barcelona (UB), Barcelona, Spain. [Comas J, Tort, J] Organització Catalana de Trasplantaments (OCATT), Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Couceiro C, Codina S, Manonelles A, Melilli E, Cruzado JM, Montero N]. Servei de Nefrologia, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Spain. Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Hospital Duran i Reynals, L’Hospitalet de Llobregat, Spain. [Favà A, Coloma A] Servei de Nefrologia, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Spain. [Lloberas N] Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Hospital Duran i Reynals, L’Hospitalet de Llobregat, Spain. [Martinez-Carbonell E] Agència de Qualitat I Avaluació Sanitàries de Catalunya (AQuAS), Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Gálvez J, Mosteiro S] Registre de Tumors Hospitalaris, Institut Català d’Oncologia (ICO), Hospitalet de Llobregat, Spain. [Borràs JM] Pla Contra el Càncer de Catalunya, Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. Departament de Ciències Clíniques, Universitat de Barcelona (UB), Barcelona, Spain
Departament de Salut
2025-05-26T07:48:46Z
2025-05-26T07:48:46Z
2025-03-20
Cancer epidemiology; Dialysis; Kidney failure; Kidney transplant
Epidemiología del cáncer; Diálisis; Insuficiencia renal; Trasplante de riñón
Epidemiologia del càncer; Diàlisi; Insuficiència renal; Trasplantament de ronyó
People with kidney failure have a higher risk of cancer compared with age- and sex-matched individuals in the general population, yet data from southern Europe are limited. This study explores cancer incidence in the kidney failure population in Catalonia. We identified cancer cases through linkage of the Catalan Kidney Registry with Catalan cancer databases. Standardized incidence ratios (SIRs) were calculated for all-site and site-specific cancers in people on dialysis and kidney transplant recipients. We described the epidemiology of cancer in 21 595 people on dialysis and 8037 kidney transplant recipients in Catalonia (2003-21). Cancer risk was more than two times higher in people on dialysis (SIR 2.11, 95% CI 2.02-2.19) and nearly four times higher in kidney transplant recipients (SIR 3.82, 95% CI 3.65-3.99) compared with the general population. Risks varied by cancer site, with a significantly higher incidence of kidney and thyroid cancers in the dialysis cohort, and skin cancer in the transplant cohort. The highest cancer risks were observed in the youngest, those with glomerular diseases, and those with the longest time since transplantation. People with kidney failure face a high burden of cancer, particularly after kidney transplantation. Understanding the epidemiology of cancer in the kidney failure population is crucial for shaping health policies.
This research was supported by a grant from the Spanish Government Instituto de Salud Carlos III (ISCIII) RICORS 2040 RD24/0004/0027 under the auspices of European Union— NextGenerationEU funds, Mecanismo para la Recuperación y la Resiliencia (MRR). L.O. was supported by a Río Hortega Fellowship, provided by the Carlos III Health Institute (ICSIII), Spain (CM23/00124).
Article
Published version
English
Insuficiència renal aguda; Càncer - Catalunya - Estadístiques; Càncer - Epidemiologia; Càncer - Factors de risc; DISEASES::Neoplasms; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Therapeutics::Sorption Detoxification::Renal Dialysis; DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency, Chronic; DISEASES::Female Urogenital Diseases and Pregnancy Complications::Female Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency, Chronic; Catalonia; ENFERMEDADES::neoplasias; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapéutica::desintoxicación por adsorción::diálisis renal; ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales::insuficiencia renal::insuficiencia renal crónica::fallo renal crónico; ENFERMEDADES::enfermedades de los genitales femeninos y complicaciones del embarazo::enfermedades urogenitales femeninas::enfermedades urológicas::enfermedades renales::insuficiencia renal::insuficiencia renal crónica::fallo renal crónico; Cataluña
Oxford University Press
Clinical Kidney Journal;18(4)
https://www.doi.org/10.1093/ckj/sfaf077
Attribution-NonCommercial 4.0 International
https://creativecommons.org/licenses/by/4.0/
