dc.contributor
Institut Català de la Salut
dc.contributor
[Belahnech Y, Calvo-Barceló M, Ródenas-Alesina E] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Martí-Aguasca G, García del Blanco B, Barrabés JA] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain. [Dos-Subirà L, Pijuan-Domènech A, Miranda B, González-Fernández V] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain. European Reference Network for Rare, Low-Prevalence, Or Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, Netherlands. [Betrian-Blasco P, Gran F, Ferrer Q, Giralt-García G, Roses-Noguer F] European Reference Network for Rare, Low-Prevalence, Or Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, Netherlands. Servei de Cardiologia Pediàtrica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Gordon B] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Baellaterra, Spain. European Reference Network for Rare, Low-Prevalence, Or Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, Netherlands. Cardiology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. [Ferreira-González I] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Martí Aguasca, Gerard
dc.contributor.author
Ferrer Menduiña, Queralt
dc.contributor.author
Giralt-Garcia, Gemma
dc.contributor.author
Gonzalez Fernandez, Victor
dc.contributor.author
Ferreira González, Ignacio
dc.contributor.author
Belahnech, Yassin
dc.contributor.author
DOS SUBIRA, LAURA
dc.contributor.author
Betrián Blasco, Pedro
dc.contributor.author
García del Blanco, Bruno
dc.contributor.author
Calvo-Barceló, Maria
dc.contributor.author
Ródenas-Alesina, Eduard
dc.contributor.author
Pijuan-Domenech, Antonia
dc.contributor.author
Gran, Ferran
dc.contributor.author
Miranda, Berta
dc.contributor.author
Gordon Ramirez, Blanca
dc.contributor.author
Barrabés, José A.
dc.contributor.author
Roses-Noguer, Ferran
dc.date.accessioned
2025-05-03T13:42:27Z
dc.date.available
2025-05-03T13:42:27Z
dc.date.issued
2025-03-20T12:19:53Z
dc.date.issued
2025-03-20T12:19:53Z
dc.date.issued
2025-02-01
dc.identifier
Belahnech Y, Martí-Aguasca G, Dos-Subirà L, Betrian-Blasco P, García del Blanco B, Calvo-Barceló M, et al. Mid-term outcomes of percutaneous pulmonary valve replacement with Edwards-Sapien bioprosthesis in native right ventricular outflow tract. Sci Rep. 2025 Feb 1;15:3977.
dc.identifier
http://hdl.handle.net/11351/12799
dc.identifier
10.1038/s41598-024-82336-4
dc.identifier
001412657900034
dc.identifier.uri
http://hdl.handle.net/11351/12799
dc.description.abstract
Congenital heart disease; Edwards sapien; Pulmonary valve
dc.description.abstract
Cardiopatia congènita; Edwards Sapien; Vàlvula pulmonar
dc.description.abstract
Cardiopatía congénita; Edwards Sapien; Válvula pulmonar
dc.description.abstract
Information on mid-term outcomes of percutaneous pulmonary valve replacement (PPVR) with the Edwards Sapien (ES) valve in the native right ventricular outflow tract (RVOT) are limited. This study assesses mid-term outcomes in 76 patients who underwent PPVR between 2016 and 2022, comparing native (40.8%) and non-native (59.2%) RVOTs. The primary endpoint was a composite of endocarditis, reinterventions, and cardiovascular death and secondary outcomes included prosthetic valve dysfunction (PVD), tricuspid regurgitation (TR), right ventricular ejection fraction (RVEF), and indexed ventricular volumes. The median patient age was 23.9 years. Pulmonary regurgitation was predominant in the native RVOT group (67.7%), while pulmonary stenosis or combined lesions were more common in the non-native group (90.9%). Procedural success was 98.7%. After a median follow-up of 3.3 years, there was no significant difference in freedom from the primary outcome between groups (87.1% native vs. 93.1% non-native, p = 0.875). Endocarditis and reinterventions occurred at 1.2 per 100 patient-years, and PVD at 3.19 per 100 patient-years, with no differences between groups. A 1-year reduction in ventricular volumes and TR was seen only in the non-native group, with no improvement in RVEF. Overall, PPVR with the ES valve demonstrates satisfactory mid-term outcomes in both native and non-native RVOTs.
dc.description.abstract
Yassin Belahnech is supported by a research non-conditioned grant (Rio Hortega CM22/00242) unrelated to the content of this article.
dc.format
application/pdf
dc.publisher
Nature Portfolio
dc.relation
Scientific Reports;15
dc.relation
https://doi.org/10.1038/s41598-024-82336-4
dc.relation
info:eu-repo/grantAgreement/ES/PEICTI2021-2023/CM22%2F00242
dc.rights
Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Avaluació de resultats (Assistència sanitària)
dc.subject
Pròtesis valvulars cardíaques
dc.subject
Cor - Vàlvules - Malalties - Cirurgia
dc.subject
NAMED GROUPS::Persons::Age Groups::Child
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Equipment and Supplies::Prostheses and Implants::Bioprosthesis
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Cardiac Surgical Procedures::Heart Valve Prosthesis Implantation
dc.subject
DISEASES::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases::Pulmonary Valve Insufficiency
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment Outcome
dc.subject
DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::niño
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::equipos y suministros::prótesis e implantes::bioprótesis
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos quirúrgicos cardiovasculares::procedimientos quirúrgicos cardíacos::implantación de prótesis valvulares cardíacas
dc.subject
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::enfermedades de las válvulas cardíacas::insuficiencia de la válvula pulmonar
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamiento
dc.title
Mid-term outcomes of percutaneous pulmonary valve replacement with Edwards-Sapien bioprosthesis in native right ventricular outflow tract
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
