Enhancing linkage to care for hepatitis B, D, and C patients: A retrospective-prospective study

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Institut Català de la Salut
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[Vargas-Accarino E, Feliu-Prius A, Barreira A, Ruiz-Cobo JC] Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain. Grup de Recerca de les Malalties Hepàtiques, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Rando-Segura A] Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Palom A] Grup de Recerca de les Malalties Hepàtiques, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBERehd, enfermedades hepáticas y digestivas, Madrid, Spain. [Martínez-Campreciós J, Romero-Vico J, Llaneras J] Grup de Recerca de les Malalties Hepàtiques, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Riveiro-Barciela M, Esteban R, Buti M] Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain. Grup de Recerca de les Malalties Hepàtiques, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBERehd, enfermedades hepáticas y digestivas, Madrid, Spain. Servei d’Hepatologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Rodríguez-Frías F] Grup de Recerca de les Malalties Hepàtiques, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain
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Vall d'Hebron Barcelona Hospital Campus
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Barreira Diaz, Ana
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Romero-Vico, Judit
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Llaneras Artigues, Jordi
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esteban, rafael
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Vargas-Accarino, Elena
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Rando Segura, Ariadna
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Palom, Adriana
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Feliu-Prius, Anna
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Martínez-Campreciós, Joan
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Ruiz Cobo, Juan Carlos
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Riveiro-Barciela, Mar
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RODRIGUEZ-FRIAS, FRANCISCO
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Buti Ferret, Maria
dc.date.accessioned
2025-02-22T17:42:49Z
dc.date.available
2025-02-22T17:42:49Z
dc.date.issued
2025-02-18T13:40:17Z
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2025-02-18T13:40:17Z
dc.date.issued
2024-11
dc.identifier
Vargas-Accarino E, Rando-Segura A, Palom A, Feliu-Prius A, Martínez-Campreciós J, Barreira A, et al. Enhancing linkage to care for hepatitis B, D, and C patients: A retrospective-prospective study. Aliment Pharmacol Ther. 2024 Nov;60(10):1308–14.
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1365-2036
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https://hdl.handle.net/11351/12624
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10.1111/apt.18227
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39192590
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001299658700001
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http://hdl.handle.net/11351/12624
dc.description.abstract
Patient care; Hepatitis B; Hepatitis D
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Atención a los pacientes; Hepatitis B; Hepatitis D
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Atenció als pacients; Hepatitis B; Hepatitis D
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Background The WHO has set a goal to decrease viral hepatitis-related fatalities by 65% by 2030. Aims To locate and retrieve to care all individuals diagnosed with hepatitis B, D or C, and investigate why they were not linked to appropriate medical management. Methods We conducted a retrospective-prospective search for patients with hepatitis B, D or C virus (HBV, HDV and HCV) infection in the central laboratory database of the Barcelona northern health area (catchment population, 450,000). We reviewed records and contacted candidates for retrieval who were offered a specialist medical visit. Results We reviewed records of 3731 patients with viral hepatitis (January 2019–December 2022): 1763 HBsAg+, 69 anti-HDV+ and 1899 HCV-RNA+. Among these, 644 (37%) HBV, 20 (29%) HDV and 1116 (56%) HCV patients were not currently linked to care. The proportion of patients receiving appropriate care was higher in HBV and HDV (p < 0.0001), and a higher percentage of unlinked hepatitis C patients had low life expectancy/comorbidities (39%; p < 0.0001). After implementing the linkage strategy, 254 HBV, 16 HDV and 54 HCV patients were successfully reintegrated into care. Among 1780 patients requiring linkage, 638 (35.8%) had moved to another health area or were missing essential contact data. Conclusions Among patients with viral hepatitis who required appropriate specialist care and were eligible for contact, 64% with HBV, 100% with HDV and 27% with HCV were successfully reintegrated into care. Overall, 324 (47.2%) eligible patients were linked to care, indicating the success of this strategy.
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This work was supported by an unrestricted grant from Gilead Sciences and by Instituto de Salud Carlos III (ISCIII) (PI23/01065).
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application/pdf
dc.language
eng
dc.publisher
Wiley
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Alimentary Pharmacology & Therapeutics;60(10)
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https://doi.org/10.1111/apt.18227
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info:eu-repo/grantAgreement/ES/PEICTI2021-2023/PI23%2F01065
dc.rights
Attribution-NonCommercial-NoDerivatives 4.0 International
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http://creativecommons.org/licenses/by-nc-nd/4.0/
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info:eu-repo/semantics/openAccess
dc.source
Scientia
dc.subject
Hepatitis B
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Hepatitis C
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Assistència sanitària
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DISEASES::Digestive System Diseases::Liver Diseases::Hepatitis::Hepatitis, Viral, Human::Hepatitis B
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DISEASES::Digestive System Diseases::Liver Diseases::Hepatitis::Hepatitis, Viral, Human::Hepatitis C
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DISEASES::Digestive System Diseases::Liver Diseases::Hepatitis::Hepatitis, Viral, Human::Hepatitis D
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HEALTH CARE::Health Services Administration::Patient Care Management
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ENFERMEDADES::enfermedades del sistema digestivo::enfermedades hepáticas::hepatitis::hepatitis viral humana::hepatitis B
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ENFERMEDADES::enfermedades del sistema digestivo::enfermedades hepáticas::hepatitis::hepatitis viral humana::hepatitis C
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ENFERMEDADES::enfermedades del sistema digestivo::enfermedades hepáticas::hepatitis::hepatitis viral humana::hepatitis D
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ATENCIÓN DE SALUD::administración de los servicios de salud::gestión de la atención al paciente
dc.title
Enhancing linkage to care for hepatitis B, D, and C patients: A retrospective-prospective study
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion


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