dc.contributor
Institut Català de la Salut
dc.contributor
[Bartels M] Department of Medical Oncology, Praxis für Onkologie Mönchengladbach, Mönchengladbach, Germany. [Chibaudel B] Department of Medical Oncology, Hôpital Franco-Britannique-Fondation Cognacq-Jay, Cancérologie ParisOuest, Levallois-Perret, France. [Dienstmann R] Oncology Data Science (ODysSey) Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. University of Vic-Central University of Catalonia, Vic, Spain. Oncoclínicas, São Paulo, Brazil. [Lehtiö J] Science for Life Laboratory and Karolinska Comprehensive Cancer Center, Department of Oncology and Pathology, Karolinska Institutet, Solna, Sweden. [Piccolo A] Pathology Unit 2, Department of Diagnostic Innovation, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. [Michielin O] Department of Oncology and the Precision Oncology Service, Geneva University Hospital, Geneva, Switzerland
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Bartels, Marius
dc.contributor.author
Chibaudel, Benoist
dc.contributor.author
Dienstmann, Rodrigo
dc.contributor.author
Lehtiö, Janne
dc.contributor.author
Piccolo, Alberta
dc.contributor.author
Michielin, Olivier
dc.date.accessioned
2025-10-25T05:38:25Z
dc.date.available
2025-10-25T05:38:25Z
dc.date.issued
2025-02-17T13:41:51Z
dc.date.issued
2025-02-17T13:41:51Z
dc.identifier
Bartels M, Chibaudel B, Dienstmann R, Lehtiö J, Piccolo A, Michielin O, et al. Evolving and Improving the Sustainability of Molecular Tumor Boards: The Value and Challenges. Cancers (Basel). 2024 Aug;16(16):2888.
dc.identifier
https://hdl.handle.net/11351/12606
dc.identifier
10.3390/cancers16162888
dc.identifier
001307319300001
dc.identifier.uri
http://hdl.handle.net/11351/12606
dc.description.abstract
Molecular tumor board; Molecularly guided therapy; Precision oncology
dc.description.abstract
Comité de tumores moleculares; Terapia guiada molecularmente; Oncología de precisión
dc.description.abstract
Comité de tumors moleculars; Teràpia guiada molecularment; Oncologia de precisió
dc.description.abstract
The increasing volume of information for cancer care, and the evolution of molecularly guided therapies, have increased the need for molecular tumor boards (MTBs), which can integrate such data into personalized treatment plans to improve patient outcomes. However, recommendations for improving the sustainability of MTBs are lacking. A diverse committee of MTB experts was assembled (February-March 2023), with extensive experience in sustainability in healthcare ecosystems. The aim was to identify MTB-related hurdles throughout the patient journey and develop a general framework for MTBs to operate on larger scales locally, nationally, and internationally. The committee identified ten key pillars for sustainable and scalable MTBs, including technical solutions for data integration and visualization, interoperability, learning loops, clinical trial access, legal considerations, criteria for patient testing, decision standardization, making MTBs official bodies for treatment decisions, local leaders, and international networks. The need for scalable frameworks at academic and community levels was recognized, along with integrating MTBs into national health systems to enhance sustainability and ensure optimal treatment decisions. Irrespective of the health ecosystem, the sustainability and scalability of MTBs are essential. Our framework provides guidelines to address this and to help MTBs evolve towards integrated, essential components of the oncology healthcare system.
dc.description.abstract
The APC was funded by F. Hoffmann-La Roche Ltd.
dc.format
application/pdf
dc.relation
Cancers;16(16)
dc.relation
https://doi.org/10.3390/cancers16162888
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Càncer - Tractament
dc.subject
Medicina personalitzada
dc.subject
DISEASES::Neoplasms
dc.subject
Other subheadings::Other subheadings::/therapy
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Precision Medicine
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DISCIPLINES AND OCCUPATIONS::Health Occupations::Medicine::Internal Medicine::Medical Oncology
dc.subject
Other subheadings::Other subheadings::/organization & administration
dc.subject
ENFERMEDADES::neoplasias
dc.subject
Otros calificadores::Otros calificadores::/terapia
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::medicina de precisión
dc.subject
DISCIPLINAS Y OCUPACIONES::profesiones sanitarias::medicina::medicina interna::oncología médica
dc.subject
Otros calificadores::Otros calificadores::/organización & administración
dc.title
Evolving and Improving the Sustainability of Molecular Tumor Boards: The Value and Challenges
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
