dc.contributor
Institut Català de la Salut
dc.contributor
[Zakrocka I] Department of Nephrology, Medical University of Lublin, Lublin, Poland. [Nair G, Jhaveri KD] Northwell Health, New York, NY, United States. Division of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Glomerular Center at Northwell Health, New York, NY, United States. [Soler MJ] Servei de Nefrologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Grup de Recerca de Nefrologia i Trasplantament Renal, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Kronbichler A] Department of Internal Medicine IV, Nephrology and Hypertension, Medical University Innsbruck, Innsbruck, Austria
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Zakrocka, Izabela
dc.contributor.author
Nair, Gayatri
dc.contributor.author
Jhaveri, Kenar D
dc.contributor.author
Kronbichler, Andreas
dc.contributor.author
Soler, María José
dc.date.accessioned
2024-11-01T02:59:37Z
dc.date.available
2024-11-01T02:59:37Z
dc.date.issued
2024-10-04T07:42:05Z
dc.date.issued
2024-10-04T07:42:05Z
dc.date.issued
2024-07-25
dc.identifier
Zakrocka I, Nair G, Soler MJ, Jhaveri KD, Kronbichler A. Paraneoplastic Syndrome After Kidney Transplantation: Frequency, Risk Factors, Differences to Paraneoplastic Occurrence of Glomerulonephritis in the Native Kidney, and Implications on Long-Term Kidney Graft Function. Transpl Int. 2024 Jul 25;37:12969.
dc.identifier
https://hdl.handle.net/11351/12011
dc.identifier
10.3389/ti.2024.12969
dc.identifier
001285382400001
dc.identifier.uri
http://hdl.handle.net/11351/12011
dc.description.abstract
Glomerulonephritis; Paraneoplastic syndrome; Transplantation
dc.description.abstract
Glomerulonefritis; Síndrome paraneoplàsica; Ttrasplantament
dc.description.abstract
Glomerulonefritis; Síndrome paraneoplásico; Trasplante
dc.description.abstract
Posttransplant malignancies are an important complication of solid organ transplantation. Kidney transplant recipients are at particularly high risk of cancer development. The most relevant risk factors of carcinogenesis are the use of immunosuppressive agents and oncogenic viral infections. Additionally, immune dysregulation caused by these factors may predispose to various types of organ damage. Paraneoplastic glomerular diseases are one of the most interesting and understudied cancer manifestations. The appropriate diagnosis of paraneoplastic glomerular damage can be challenging in kidney transplant recipients, due to factors inherent to concomitant medication and common comorbidities. Recent advances in the field of molecular and clinical nephrology led to a significant improvement in our understanding of glomerular diseases and their more targeted treatment. On the other hand, introduction of novel anticancer drugs tremendously increased patients’ survival, at the cost of kidney-related side effects. Our review aims to provide insights into diagnosis and treatment of paraneoplastic glomerular diseases, with a special attention to kidney transplant recipients.
dc.description.abstract
The authors declare that financial support was received for the research, authorship, and/or publication of this article. MS is supported by grants from Fondo de Investigación Sanitaria-FEDER, ISCIII, PI17/00257, PI20/00744, PI21/01292, Marató TV3 2020 421/C/2020, Marató TV3 2021 215/C/2021, RD16/0009/0030 (REDINREN), BECA SENFRO 2021, RD21/0005/0016 (RICORS 2040), and ERA-PerMed-JTC 2022 (ONAKI-ICI AC22/00029).
dc.format
application/pdf
dc.publisher
Frontiers Media
dc.relation
Transplant International;37
dc.relation
https://doi.org/10.3389/ti.2024.12969
dc.relation
info:eu-repo/grantAgreement/ES/PE2017-2020/PI17%2F00257
dc.relation
info:eu-repo/grantAgreement/ES/PEICTI2021-2023/PI21%2F01292
dc.relation
info:eu-repo/grantAgreement/ES/PEICTI2021-2023/AC22%2F00029
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Glomerulonefritis
dc.subject
Medicaments immunosupressors - Ús terapèutic - Efectes secundaris
dc.subject
Càncer - Factors de risc
dc.subject
Ronyons - Trasplantació - Complicacions
dc.subject
DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Nephritis::Glomerulonephritis
dc.subject
CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Immunosuppressive Agents
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Transplantation::Organ Transplantation::Surgical Procedures, Operative::Kidney Transplantation
dc.subject
DISEASES::Neoplasms::Paraneoplastic Syndromes
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
dc.subject
ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales::nefritis::glomerulonefritis
dc.subject
COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::efectos fisiológicos de los fármacos::factores inmunitarios::inmunosupresores
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::trasplante::trasplante de órganos::intervenciones quirúrgicas::trasplante de riñón
dc.subject
ENFERMEDADES::neoplasias::síndromes paraneoplásicos
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo
dc.title
Paraneoplastic Syndrome After Kidney Transplantation: Frequency, Risk Factors, Differences to Paraneoplastic Occurrence of Glomerulonephritis in the Native Kidney, and Implications on Long-Term Kidney Graft Function
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
