dc.contributor
Institut Català de la Salut
dc.contributor
[Mitsikostas DDD] Neurology Department, Aeginition Hospital, Medical School, National & Kapodistrian University of Athens, Athens, Greece. [Caronna E, Pozo-Rosich P] Unitat de Cefalees, Servei de Neurologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca de Cefalea i Dolor Neurològic, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. [De Tommaso M] Neurophysiopathology Unit, DiBrain Department, Aldo Moro University, Bari, Italy. [Deligianni CI] Athens Naval Hospital, Athens, Greece. [Ekizoglu E] Department of Neurology, Faculty of Medicine, Istanbul University, Istanbul, Istanbul, Turkey. [Bolay H] Department of Neurology and Algology, NÖROM, Gazi University Ankara, Ankara, Turkey
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
DE TOMMASO, MARINA
dc.contributor.author
Deligianni, Christina
dc.contributor.author
Ekizoglu, Esme
dc.contributor.author
Mitsikostas, Dimos
dc.contributor.author
Caronna, Edoardo
dc.contributor.author
Bolay, Hayrunnisa
dc.contributor.author
Pozo-Rosich, Patricia
dc.date.accessioned
2024-06-06T13:34:49Z
dc.date.available
2024-06-06T13:34:49Z
dc.date.issued
2024-05-22T06:48:53Z
dc.date.issued
2024-05-22T06:48:53Z
dc.identifier
Mitsikostas DDD, Caronna E, De Tommaso M, Deligianni CI, Ekizoglu E, Bolay H, et al. Headaches and facial pain attributed to SARS-CoV-2 infection and vaccination: a systematic review. Eur J Neurol. 2024 Jun;31(6):e16251.
dc.identifier
https://hdl.handle.net/11351/11481
dc.identifier
10.1111/ene.16251
dc.identifier
001174198400001
dc.identifier.uri
http://hdl.handle.net/11351/11481
dc.description.abstract
Chronic daily headache; Headache; Neurological disorders
dc.description.abstract
Cefalea crònica diària; Mal de cap; Trastorns neurològics
dc.description.abstract
Cefalea crónica diaria; Dolor de cabeza; Trastornos neurológicos
dc.description.abstract
Background and purpose
The aim was to provide insights to the characteristics of headache in the context of COVID-19 on behalf of the Headache Scientific Panel and the Neuro-COVID-19 Task Force of the European Academy of Neurology (EAN) and the European Headache Federation (EHF).
Methods
Following the Delphi method the Task Force identified six relevant questions and then conducted a systematic literature review to provide evidence-based answers and suggest specific diagnostic criteria.
Results
No data for facial pain were identified in the literature search. (1) Headache incidence during acute COVID-19 varies considerably, with higher prevalence rates in prospective compared to retrospective studies (28.9%–74.6% vs. 6.5%–34.0%). (2) Acute COVID-19 headache is usually bilateral or holocranial and often moderate to severe with throbbing pain quality lasting 2–14 days after first signs of COVID-19; photo-phonophobia, nausea, anosmia and ageusia are common associated features; persistent headache shares similar clinical characteristics. (3) Acute COVID-19 headache is presumably caused by immune-mediated mechanisms that activate the trigeminovascular system. (4) Headache occurs in 13.3%–76.9% following SARS-CoV-2 vaccination and occurs more often amongst women with a pre-existing primary headache; the risk of developing headache is higher with the adenoviral-vector-type vaccines than with other preparations. (5) Headache related to SARS-CoV-2 vaccination is mostly bilateral, and throbbing, pressing, jolting or stabbing. (6) No studies have been conducted investigating the underlying mechanism of headache attributed to SARS-CoV-2 vaccines.
Conclusion
The results of this joint EAN/EHF initiative provide a framework for a better understanding of headache in the context of SARS-CoV-2 infection and vaccination.
dc.format
application/pdf
dc.publisher
Wiley Open Access
dc.relation
European Journal of Neurology;31(6)
dc.relation
https://doi.org/10.1111/ene.16251
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
COVID-19 (Malaltia) - Vacunació
dc.subject
Medicaments - Efectes secundaris
dc.subject
Cefalàlgia - Epidemiologia
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Dolor facial - Epidemiologia
dc.subject
DISEASES::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections
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ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy::Immunization::Immunotherapy, Active::Vaccination
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Other subheadings::Other subheadings::Other subheadings::/adverse effects
dc.subject
DISEASES::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Neurologic Manifestations::Pain::Headache
dc.subject
DISEASES::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Neurologic Manifestations::Pain::Facial Pain
dc.subject
ENFERMEDADES::virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapia biológica::inmunomodulación::inmunoterapia::inmunización::inmunoterapia activa::vacunación
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Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos
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ENFERMEDADES::afecciones patológicas, signos y síntomas::signos y síntomas::manifestaciones neurológicas::dolor::cefalea
dc.subject
ENFERMEDADES::afecciones patológicas, signos y síntomas::signos y síntomas::manifestaciones neurológicas::dolor::dolor facial
dc.title
Headaches and facial pain attributed to SARS-CoV-2 infection and vaccination: a systematic review
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
