Sistema de Salut de Catalunya
Institut Català de la Salut
[Vrtovsnik F] Department of Nephrology, Xavier Bichat Hospital, Paris, France. [Verger C] Registre de Dialyse Péritonéale de Langue Française, Pontoise, France. [Van Biesen W] Renal Division, Ghent University Hospital, Ghent, Belgium. [Fan S] Department of Renal Medicine and Transplantation, The Royal London Hospital, London, UK. [Shin SK] Department of Internal Medicine, NHIC ILsan Hospital, Koyang, Korea. [Rodríguez C] Nephrology Service, Hospital Universitario Central de Asturia, Oviedo, Spain. [Garcia Méndez I] Servicio de Nefrología, Hospital Universitari de Girona Doctor Josep Trueta, Institut Català de la Salut (ICS), Girona, Spain
Hospital Universitari de Girona Dr Josep Trueta
2024-03-20T09:59:35Z
2024-03-20T09:59:35Z
2019-12-22
Diàlisi peritoneal; Hemodiàlisi; Estudi observacional
Diálisis peritoneal; Hemodiálisis; Estudio observacional
Peritoneal Dialysis; Hemodialysis; Cohort study
Background: Technique failure in peritoneal dialysis (PD) can be due to patient- and procedure-related factors. With this analysis, we investigated the association of volume overload at the start and during the early phase of PD and technique failure. Methods: In this observational, international cohort study with longitudinal follow-up of incident PD patients, technique failure was defined as either transfer to haemodialysis or death, and transplantation was considered as a competing risk. We explored parameters at baseline or within the first 6 months and the association with technique failure between 6 and 18 months, using a competing risk model. Results: Out of 1092 patients of the complete cohort, 719 met specific inclusion and exclusion criteria for this analysis. Being volume overloaded, either at baseline or Month 6, or at both time points, was associated with an increased risk of technique failure compared with the patient group that was euvolaemic at both time points. Undergoing treatment at a centre with a high proportion of PD patients was associated with a lower risk of technique failure. Conclusions: Volume overload at start of PD and/or at 6 months was associated with a higher risk of technique failure in the subsequent year. The risk was modified by centre characteristics, which varied among regions.
The study has been funded by Fresenius Medical Care Deutschland GmbH and Fresenius Medical Care Asia Pacific Ltd.
Article
Published version
English
Diàlisi peritoneal; Hemodiàlisi; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Renal Replacement Therapy::Renal Dialysis::Peritoneal Dialysis; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::tratamiento de reemplazo renal::diálisis renal::diálisis peritoneal; CARACTERÍSTICAS DE PUBLICACIONES::características del estudio::estudio clínico::estudio observacional
Oxford University Press
Clinical Kidney Journal;14(2)
https://doi.org/10.1093/ckj/sfz175
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
