dc.contributor
Institut Català de la Salut
dc.contributor
[Dopazo C, Charco R] Servei de Cirurgia Hepatobiliopancreàtica i Trasplantaments, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
DOPAZO, CRISTINA
dc.contributor.author
Charco, Ramon
dc.date.accessioned
2025-10-24T10:42:07Z
dc.date.available
2025-10-24T10:42:07Z
dc.date.issued
2023-08-30T10:11:42Z
dc.date.issued
2023-08-30T10:11:42Z
dc.date.issued
2023-03-29
dc.identifier
Dopazo C, Charco R. Liver Transplantation for perihilar cholangiocarcinoma. Do we need to move forward? Hepatoma Res. 2023 Mar 29;9:10.
dc.identifier
https://hdl.handle.net/11351/10179
dc.identifier
10.20517/2394-5079.2022.75
dc.identifier.uri
http://hdl.handle.net/11351/10179
dc.description.abstract
Perihilar cholangiocarcinoma; Liver transplantation; Outcomes
dc.description.abstract
Colangiocarcinoma perihilar; Trasplantament hepàtic; Resultats
dc.description.abstract
Colangiocarcinoma perihiliar; Trasplante hepático; Resultados
dc.description.abstract
Perihilar cholangiocarcinoma (pCCA) is a challenging disease with limited options. Surgical resection and adjuvant therapy remain the only established treatment for those with resectable disease. Since the publication of the Mayo protocol in 2000, neoadjuvant chemoradiation and liver transplantation have become the standard of care in selected patients with unresectable de novo pCCA or resectable pCCA arising under primary sclerosing cholangitis. However, its application is diverse worldwide, and the need for donor organs is one of the main limitations. Also, differences in the neoadjuvant regimen used were observed. In this review, we discuss the latest results of this approach, the recommended tools for diagnostic work-up, and advances in systemic therapy to improve patient selection and long-term survival.
dc.format
application/pdf
dc.publisher
OAE Publishing
dc.relation
Hepatoma Research;9
dc.relation
http://dx.doi.org/10.20517/2394-5079.2022.75
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Conductes biliars - Càncer - Tractament
dc.subject
Fetge - Trasplantació
dc.subject
DISEASES::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Glandular and Epithelial::Carcinoma::Adenocarcinoma::Cholangiocarcinoma
dc.subject
Other subheadings::Other subheadings::/therapy
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Digestive System Surgical Procedures::Surgical Procedures, Operative::Surgical Procedures, Operative::Liver Transplantation
dc.subject
DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Biliary Tract Neoplasms::Bile Duct Neoplasms
dc.subject
ENFERMEDADES::neoplasias::neoplasias por tipo histológico::neoplasias glandulares y epiteliales::carcinoma::adenocarcinoma::colangiocarcinoma
dc.subject
Otros calificadores::Otros calificadores::/terapia
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos quirúrgicos del sistema digestivo::intervenciones quirúrgicas::intervenciones quirúrgicas::trasplante de hígado
dc.subject
ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias del tracto biliar::neoplasias de los conductos biliares
dc.title
Liver Transplantation for perihilar cholangiocarcinoma. Do we need to move forward?
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
