dc.contributor.author
Capell Capell, Teresa
dc.contributor.author
Twyman, Richard M.
dc.contributor.author
Armario-Nájera, Victoria
dc.contributor.author
Ma, Julian K.-C.
dc.contributor.author
Schillberg, Stefan
dc.contributor.author
Christou, Paul
dc.date.accessioned
2026-02-16T19:12:35Z
dc.date.available
2026-02-16T19:12:35Z
dc.identifier
https://doi.org/10.1016/j.tplants.2020.04.009
dc.identifier
https://hdl.handle.net/10459.1/469587
dc.identifier.uri
http://hdl.handle.net/10459.1/469587
dc.description.abstract
The current COVID-19 pandemic has created an immediate massive demand for diagnostic reagents based on SARS-CoV-2 RNA/proteins and corresponding antibodies, placing immense strain on the supply and distribution chain.
Transient expression in plants could address the shortage by achieving rapid, larger-scale production, complemented by longer-term higher-volume production in transgenic plants.
The same technology used to produce diagnostic reagents could also be used to produce vaccine candidates (SARS-CoV-2 subunits and virus-like particles) as well as therapeutic antibodies and antiviral proteins.
It will be necessary to pool the international resources of molecular farming research groups and industry to capitalize on expertise, although distributed production using local infrastructure is the key to reaching all parts of the world.
dc.relation
Versió postprint del document publicat a: https://doi.org/10.1016/j.tplants.2020.04.009
dc.relation
Trends in Plant Science, 2020, vol. 25, núm. 7, p. 635-643
dc.rights
cc-by-nc-nd (c) Elsevier, 2020
dc.rights
Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights
info:eu-repo/semantics/openAccess
dc.rights
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject
Molecular farming
dc.subject
Transient expression
dc.title
Potential applications of plant biotechnology against SARS-CoV-2
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
