Use of cellular decapping activators by positive-strand RNA viruses

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Título:	Use of cellular decapping activators by positive-strand RNA viruses
Autor/a:	Jungfleisch, Jennifer, 1986-; Blasco Moreno, Bernat, 1986-; Díez Antón, Juana, 1962-
Abstract:	Positive-strand RNA viruses have evolved multiple strategies to not only circumvent the hostile decay machinery but to trick it into being a priceless collaborator supporting viral RNA translation and replication. In this review, we describe the versatile interaction of positive-strand RNA viruses and the 5'-3' mRNA decay machinery with a focus on the viral subversion of decapping activators. This highly conserved viral trickery is exemplified with the plant Brome mosaic virus, the animal Flock house virus and the human hepatitis C virus.
Abstract:	This work was supported by the Spanish Ministry of Economy and Competitiveness through/ngrant BFU 2013-44629-R and the “Maria de Maeztu” Programme for Units of Excellence in R&D (MDM-2014-0370)
Materia(s):	-Virus RNA -RNA missatger
Derechos:	https://creativecommons.org/licenses/by/4.0/ © 2016 by Jennifer Jungfleisch, Bernat Blasco-Moreno and Juana Díez; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)
Tipo de documento:	Artículo Artículo - Versión publicada
Editor:	MDPI
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