To access the full text documents, please follow this link: http://hdl.handle.net/2445/11512

Title:	Supplementary material to Ocaña, J., Sánchez, M.P., Sánchez, A. and Carrasco, J.L. ¿On equivalence and bioequivalence testing¿, SORT, 32(2), 2008
Author:	Ocaña i Rebull, Jordi; Sánchez Olavarría, María Pilar; Sànchez, Àlex (Sànchez Pla); Carrasco Jordan, Josep Lluís
Abstract:	Equivalence testing is the natural approach to many statistical problems. First, its main application, bioequivalence testing, is reviewed. The basic concepts of bioequivalence testing (2×2 crossover designs, TOST, interval inclusion principle, etc.) and its problems (TOST biased character, the carry- over problem, etc.) are considered. Next, equivalence testing is discussed more generally. Some applications and methods are reviewed and the relation of equivalence testing and distance-based inference is highlighted. A new distance-based method to determine whether two gene lists are equivalent in terms of their annotations in the Gene Ontology illustrates these ideas. We end with a general discussion and some suggestions for future research.
Subject(s):	-Mètodes estadístics -Equivalència terapèutica dels medicaments -Statistical methods -Therapeutic equivalency in drugs
Rights:	cc-by-nc-nd, (c) Ocaña et al., 2008 http://creativecommons.org/licenses/by-nc-nd/2.5/es/
Document type:	Working Paper
Share:

Show full item record