dc.contributor |
Universitat de Barcelona |
dc.contributor.author |
Rabassa Bonet, Montserrat |
dc.contributor.author |
Zamora-Ros, Raul |
dc.contributor.author |
Andrés Lacueva, Ma. Cristina |
dc.contributor.author |
Urpí Sardà, Mireia |
dc.contributor.author |
Bandinelli, Stefania |
dc.contributor.author |
Ferrucci, Luigi |
dc.contributor.author |
Cherubini, Antonio |
dc.date |
2016-03-14T17:12:17Z |
dc.date |
2016-10-10T22:01:17Z |
dc.date |
2015-10-10 |
dc.date |
2016-03-14T17:12:22Z |
dc.identifier.citation |
1279-7707 |
dc.identifier.citation |
655500 |
dc.identifier.uri |
http://hdl.handle.net/2445/96466 |
dc.format |
8 p. |
dc.format |
application/pdf |
dc.language.iso |
eng |
dc.publisher |
Springer Science + Business Media |
dc.relation |
Versió postprint del document publicat a: http://dx.doi.org/10.1007/s12603-015-0600-2 |
dc.relation |
Journal of Nutrition, Health & Aging, 2015 |
dc.relation |
http://dx.doi.org/10.1007/s12603-015-0600-2 |
dc.rights |
(c) Springer Science + Business Media, 2015 |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Marcadors bioquímics |
dc.subject |
Polifenols |
dc.subject |
Envelliment |
dc.subject |
Epidemiologia |
dc.subject |
Biochemical markers |
dc.subject |
Polyphenols |
dc.subject |
Aging |
dc.subject |
Epidemiology |
dc.title |
Association between both total baseline urinary and dietary polyphenols and substantial physical performance decline risk in older adults: A 9-year follow-up of the InCHIANTI study |
dc.type |
info:eu-repo/semantics/article |
dc.type |
info:eu-repo/semantics/acceptedVersion |
dc.description.abstract |
Importance: The decline in physical performance that occurs in many older subjects is a strong predictor of falls, hospitalization, institutionalization and mortality. Polyphenols are bioactive compounds that may play a preventive role against physical performance decline due to their antioxidant and anti-inflammatory properties. Objective: To investigate the association between total urinary polyphenols (TUP) and total dietary polyphenols (TDP) and substantial physical performance decline over a nine-year period among older subjects. Methods: This longitudinal study included 368 participants aged 65 years or older from the InCHIANTI (Invecchiare in Chianti) study, an Italian population-based cohort. TUP and TDP concentrations were assessed at baseline using the Folin-Ciocalteau (F-C) assay and a validated food frequency questionnaire, respectively. Physical performance was objectively measured at baseline and at nine-year follow-up using the Short Physical Performance Battery (SPPB). A substantial decline in physical performance was considered as a decrease of three or more points in the SPPB score. Results: At the nine-year follow-up assessment, 71 participants had suffered a substantial decline in physical performance. In the fully adjusted logistic regression model, participants in the highest TUP tertile had a lower risk of substantial decline in physical performance than those in the lowest tertile (OR, 0.40; 95% CI, 0.17 0.93; P trend=0.033). However, no significant association between TDP intake and physical performance decline was observed. Conclusion: This study shows that high TUP concentrations, a biomarker of polyphenol-rich exposure, were associated with lower risk of substantial decline in physical performance in community-dwelling older subjects over a nine-year period. These results suggest that a polyphenol-rich diet may play a role in protecting against physical performance decline in older people. |