Title:
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Cyclosporine A, an alternative to the oral lichen planus erosive treatment
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Author:
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López López, José, 1958-; Roselló Llabrés, Xavier
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Other authors:
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Universitat de Barcelona |
Abstract:
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We present a double-blind study in two groups afflicted with oral lichen planus erythematous of long evolution and resistant to other treatments. We tested on it a treatment with Cyclosporine A (CyA) which had been successfully used before by many dermatologists. In the group A we used mouthwashes with a 5 ml Cyclosporine A solution to a 10% in olive oil of 0.4 degrees of acidity for five minutes, three times a day for eight weeks. In the control group we used acetonide of triamcinolone 01% in aqueous solution. Patients in group A improved considerably in their symptomatology in a 90% against a 60% in group B. In group A we could appreciate a disappearance of the symptomatology after two weeks of treatment in 60% of patients against 30% in group B. CyA can be an alternative to the conventional treatments in the acute period of lichen planus although it can not be considered as a first option drug because of the high cost of the treatment. For long term, results are not so good and we consider that extensive studies are necessary |
Publication date:
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2014-07-14 |
Subject(s):
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-Ciclosporina -Higiene bucal -Higiene dental -Desinfectants -Mucosa oral -Líquens -Cyclosporine -Oral hygiene -Dental hygiene -Disinfectants -Oral mucosa -Lichens |
Rights:
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(c) Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie, 1995
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Document type:
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Article Article - Published version |
Published by:
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Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie
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