Per accedir als documents amb el text complet, si us plau, seguiu el següent enllaç: http://hdl.handle.net/2117/23005

Development and characterization of biphasic hydroxyapatite/ß-TCP cements
Gallinetti, Sara; Canal Barnils, Cristina; Ginebra Molins, Maria Pau
Universitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica; Universitat Politècnica de Catalunya. BIBITE - Biomaterials, Biomecànica i Enginyeria de Teixits
Biphasic calcium phosphate bioceramics composed of hydroxyapatite (HA) and ß-tricalcium phosphate (ß-TCP) have relevant properties as synthetic bone grafts, such as tunable resorption, bioactivity, and intrinsic osteoinduction. However, they have some limitations associated to their condition of high-temperature ceramics. In this work self-setting Biphasic Calcium Phosphate Cements (BCPCs) with different HA/ß-TCP ratios were obtained from self-setting a-TCP/ß-TCP pastes. The strategy used allowed synthesizing BCPCs with modulated composition, compressive strength, and specific surface area. Due to its higher solubility, a-TCP was fully hydrolyzed to a calcium-deficient HA (CDHA), whereas ß-TCP remained unreacted and completely embedded in the CDHA matrix. Increasing amounts of the non-reacting ß-TCP phase resulted in a linear decrease of the compressive strength, in association to the decreasing amount of precipitated HA crystals, which are responsible for the mechanical consolidation of apatitic cements. Ca2+ release and degradation in acidic medium was similar in all the BCPCs within the timeframe studied, although differences might be expected in longer term studies once ß-TCP, the more soluble phase was exposed to the surrounding media
Peer Reviewed
Àrees temàtiques de la UPC::Enginyeria dels materials
Bone cements
Engineering controlled terms: Bioceramics
Bone cement
Calcium
Compressive strength
Hydroxyapatite
Ciments ossis
Attribution-NonCommercial-NoDerivs 3.0 Spain
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
info:eu-repo/semantics/publishedVersion
Article
         

Mostra el registre complet del document

Documents relacionats

Altres documents del mateix autor/a

Canal Barnils, Cristina; Khurana, Kanupriya; Labay, Cedric Pierre; Gallinetti, Sara; Ginebra Molins, Maria Pau
Gallinetti, Sara; Mestres, Gemma; Canal Barnils, Cristina; Persson, Cecilia; Ginebra Molins, Maria Pau
Canal Barnils, Cristina; Khurana, Kanupriya; Gallinetti, Sara; Bhatt, Sudhir; Pulpytel, Jerome; Arefi Khonsari, Farzaneh; Ginebra Molins, Maria Pau
Lee, So-Youn; Yun, Hyung-Mun; Pérez Antoñanzas, Román; Gallinetti, Sara; Ginebra Molins, Maria Pau; Choi, Seong-Jun; Kim, Hae-Won; Kim, Eun-Cheol