Contamination of genomic databases by HIV-1 and its possible consequences. A study in Bioinformatics.

All of RECERCAT

To access the full text documents, please follow this link: http://hdl.handle.net/10609/31361

Title:	Contamination of genomic databases by HIV-1 and its possible consequences. A study in Bioinformatics.
Author:	Romero Fernández-Bravo, Miguel Ángel
Abstract:	Peer-reviewed
Abstract:	The bioinformatics Basic Local Alignment Search Tools (BLASTN and TBLASTN) were used to search public databases for nucleic acid (NA) and amino acid (AA) sequences identical or similar to HIV-1 DNA and proteins. Several significant alignments were detected in a variety of non-HIV-1 taxa and other sources deposited in public genomic and protein repositories. Homologies between a number of HIV-1 proteins and those of Candida, Cryptococcus and Schistosoma mansoni are of uncertain significance and suggest the need for further analyses. The overwhelmingly likely cause for these data is contamination.
Subject(s):	-HIV-1 -BLASTN -Genomic -Contamination -VIH-1 -bioinformatics -bioinformàtica -bioinformática
Rights:	http://creativecommons.org/licenses/by-nc-sa/3.0/es/
Document type:	Article
Share:

Coordination

Supporters