Title:
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Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops
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Author:
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Benabou, Sanae; Ferreira Aguilera, Rubén; Aviñó Andrés, Anna; González, Carlos; Lyonnais, Sébastien; Solà Vilarrubias, Maria; Eritja i Casadellà, Ramon; Jaumot Soler, Joaquim; Gargallo Gómez, Raimundo
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Other authors:
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Universitat de Barcelona |
Abstract:
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Cytosine-and guanine-rich regions of DNA are capable of forming complex structures named i-motifs and G-quadruplexes, respectively. In the present study the solution equilibria at nearly physiological conditions of a 34 -bases long cytosine-rich sequence and its complementary guanin e-rich strand corresponding to the first intron of the n-mycgene were studied. Both sequences , not yet studied, contain a 12 - base tract capable of forming stable hairpins inside the i-motif and G-quadruplex structures, respectively ... |
Subject(s):
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-ADN -RNA -Àcids nucleics -Anàlisi multivariable -Cromatografia -DNA -RNA -Nucleic acids -Multivariate analysis -Chromatography |
Rights:
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(c) Elsevier B.V., 2013
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Document type:
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Article Article - Accepted version |
Published by:
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Elsevier B.V.
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