Title:
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An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines
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Author:
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Amat Tusón, Mercedes; Pérez Bosch, Maria; Minaglia, Annamaria T.; Bosch Cartes, Joan
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Other authors:
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Universitat de Barcelona |
Abstract:
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A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position. |
Subject(s):
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-Compostos organometàl·lics -Coure -Síntesi orgànica -Lactames -Organometallic compounds -Copper -Synthetic organic chemistry -Lactams |
Rights:
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(c) American Chemical Society , 2008
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Document type:
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Article Article - Accepted version |
Published by:
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American Chemical Society
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