dc.contributor.author |
Oromí Farrús, Mireia |
dc.contributor.author |
Eras i Joli, Jordi |
dc.contributor.author |
Sala i Martí, Núria |
dc.contributor.author |
Torres i Grifo, Mercè |
dc.contributor.author |
Canela i Garayoa, Ramon |
dc.date |
2010-04-30T12:43:05Z |
dc.date |
2010-04-30T12:43:05Z |
dc.date |
2009 |
dc.identifier |
1420-3049 |
dc.identifier |
http://hdl.handle.net/10459.1/370 |
dc.identifier |
https://doi.org/10.3390/molecules14104275 |
dc.identifier.uri |
http://hdl.handle.net/10459.1/370 |
dc.description |
Preparation of (S)-1-chloro-2-octanol and (S)-1-bromo-2-octanol was carried out by the enzymatic hydrolysis of halohydrin palmitates using biocatalysts. Halohydrin
palmitates were prepared by various methods from palmitic acid and 1,2-octanediol. A
tandem hydrolysis was carried out using lipases from Candida antarctica (Novozym® 435),
Rhizomucor miehei (Lipozyme IM), and “resting cells” from a Rhizopus oryzae strain that was not mycotoxigenic. The influence of the enzyme and the reaction medium on the selective hydrolysis of isomeric mixtures of halohydrin esters is described. Novozym® 435 allowed preparation of (S)-1-chloro-2-octanol and (S)-1-bromo-2-octanol after 1–3 h ofreaction at 40 °C in [BMIM][PF6]. |
dc.language |
eng |
dc.publisher |
Molecular Diversity Preservation International |
dc.relation |
Reproducció del document publicat a https://doi.org/10.3390/molecules14104275 |
dc.relation |
Molecules, 2009, vol. 14, núm. 10, p. 4275-4283 |
dc.rights |
cc-by, (c) Oromí-Farrús et al., 2009 |
dc.rights |
http://creativecommons.org/licenses/by/3.0/es/deed.ca |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
(S)-1-bromomethyl-1-heptanol |
dc.subject |
(S)-1-chloromethyl-1-heptanol |
dc.subject |
Lipases |
dc.subject |
Enzymatic resolution |
dc.subject |
Lipasa |
dc.title |
Preparation of (S)-1-halo-2-octanols using ionic liquids and biocatalysts |
dc.type |
article |
dc.type |
publishedVersion |