https://hdl.handle.net/2072/1057 www.ub.edu Wed, 15 Apr 2026 07:12:48 GMT 2026-04-15T07:12:48Z http://recercat.cat:80/bitstream/id/f207ef4c-450a-4af0-8a78-bcb1af7922d5/ https://hdl.handle.net/2072/1057 https://hdl.handle.net/2445/228907 Identifying chronotype for the preservation of muscle mass, quality and strength Barrientos-Salinas, R.; Dahdah, N.; Alvarez-Luis, J.; Vilarrasa, Nuria; García-Roves, Pablo M. (Pablo Miguel) Chronotype, an individual’s preferred timing of sleep and activity within a 24 h cycle, significantly influences metabolic health, muscle function, and body composition. This review explores the interplay between circadian rhythms, hormonal fluctuations, and behavioral patterns—such as nutrition timing, physical activity and sleep quality—and their impact on muscle mass, strength, and quality. Evening chronotypes (ETs) are consistently associated with poorer sleep, irregular eating habits, reduced physical activity, and increased risk of obesity, sarcopenia and metabolic disorders compared to morning types (MTs). At the molecular level, disruptions in circadian clock gene expression (e.g., BMAL1, PER2, CRY1) affect protein synthesis, insulin sensitivity, and energy metabolism, contributing to muscle degradation and impaired recovery. The review highlights critical components—targeting chrono-nutrition, sleep quality, and exercise timing—to align lifestyle behaviors with circadian biology, thereby preserving muscle health and improving overall metabolic outcomes. Tue, 14 Apr 2026 12:51:40 GMT https://hdl.handle.net/2445/228907 2026-04-14T12:51:40Z https://hdl.handle.net/2445/228846 Mirar l'improbable Bueno i Torrens, David, 1965- Pot semblar que els esports d’equip i la física quàntica no tenen res en comú, però com succeeix amb les partícules subatòmiques, la connexió invisible entre els jugadors és la que crea una força extraordinària capaç de transformar el resultat més improbable en una victòria compartida. Per això aquest mes us apropo dos llibres que, malgrat que pugui semblar tot el contrari, tenen més punts en comú del que sembla: la potència formadora dels esports d’equip i la creadora de realitats de la física quàntica. Mon, 13 Apr 2026 06:21:10 GMT https://hdl.handle.net/2445/228846 2026-04-13T06:21:10Z https://hdl.handle.net/2445/228851 Navigating spatio-temporal microbiome dynamics: Environmental factors and trace elements shape the symbiont community of an invasive marine species Galià Camps, Carles; Junkin, Liam; Borrallo, Xavier; Carreras Huergo, Carlos; Pascual Damieta, Marta; Turon Barrera, Xavier The proliferation of marine invasive species is a mounting concern. While the role of microbial communities in invasive ascidian species is recognized, the role of seasonal shifts in microbiome composition remains largely unexplored. We sampled five individuals of the invasive ascidian Styela plicata quarterly from January 2020 to October 2021 in two harbours, examining gills, tunics, and surrounding water. By analysing Amplicon Sequence Variants (ASVs) and seawater trace elements, we found that compartment (seawater, tunic, or gills) was the primary differentiating factor, followed by harbour. Clear seasonal patterns were evident in seawater bacteria, less so in gills, and absent in tunics. We identified compartment-specific bacteria, as well as seasonal indicator ASVs and ASVs correlated with trace element concentrations. Among these bacteria, we found that Endozoicomonas, Hepatoplasma and Rhodobacteraceae species had reported functions which might be necessary for overcoming seasonality and trace element shifts. This study contributes to understanding microbiome dynamics in invasive holobiont systems, and the patterns found indicate a potential role in adaptation and invasiveness. Mon, 13 Apr 2026 07:18:09 GMT https://hdl.handle.net/2445/228851 2026-04-13T07:18:09Z https://hdl.handle.net/2445/228849 Modulation of the gut microbiome-adipose tissue axis by maqui supplementation improved insulin resistance and lipid metabolism in mice under a high-fat diet. Tume, Rafael; Cruz, Meryl; Sandoval, Viviana; Iglesias-Vejar, Lorena; Sanz Lamora, Héctor; Pérez-Martí, A.; Torres-Oteros, Daniel; Cubedo-Cullere, Marta; Carmona Pontaque, Francesc; Martínez Huélamo, Miriam; Marrero González, Pedro F.; Haro, D.; Canudas Puig, Sílvia; Andrés Lacueva, Ma. Cristina; Relat, Joana; Meroño, Tomás To assess the impact of maqui (Aristotelia chilensis) supplementation on the gut microbiome-adipose tissue axis, and to associate it with gene expression changes in white adipose tissue (WAT) in mice fed a high-fat diet. Our hypothesis is that the gut microbiome-adipose tissue axis will be involved in Maqui's effect on WAT browning. Twenty-nine 4-week-old C57BL/6 J mice were randomly assigned to a high-fat diet (HFD, n = 15) or HFD + Maqui (n = 14) for 16 weeks. Plasma samples were analyzed using an UPLC-QTRAP exposome-based metabolomics method. Gut microbiome was studied by fecal 16S rRNA gene sequencing. Gene expression in WAT was assessed by real-time PCR. Data were analyzed by multivariate methods and integrated through multiomics analyses. Maqui supplementation induced an increase in Lactobacillus, Lactococcus and Bifidobacterum and a reduction in Desulfovibrium, and Acetatifactor. Out of 19 metabolites altered by maqui supplementation, 9 were derived from gut bacterial fermentation of anthocyanins. Increases in L. gasseri and L. johnsonii in the gut were associated to increased production of phenyllactic acid, 4-O-methylgallic acid, and 3-(3′-hydroxyphenyl)-γ-valerolactone. Integrative analysis revealed a concerted role of Lactobacillus spp. and its ability to ferment maqui polyphenols, along with increased expression of Chrebpb, Pgc1a and Ucp1 in WAT. Enrichment of Lactobacillus gasseri and johnsonii and exposure to 2-hydroxybenzoic acid derived from polyphenols fermentation are evidences of the involvment of the gut-microbiome-adipose tissue axis in WAT browning induced by maqui. Mon, 13 Apr 2026 06:58:52 GMT https://hdl.handle.net/2445/228849 2026-04-13T06:58:52Z