https://hdl.handle.net/2072/484352 2026-04-06T17:44:27Z https://hdl.handle.net/20.500.12328/5281 Sustainability in the Mission Statements of Argentine Higher Education Institutions ARIAS VALLE, MARIA BELEN; Marimon, Frederic This study examines the integration of sustainability in the mission statements of Argentine Higher Education Institutions (HEIs). Using a qualitative approach, the study analyzes both public and private universities through semiotic and discourse analysis. Results indicate that only 15% of HEIs explicitly mention sustainability in their missions, with significant differences between public and private institutions. Public HEIs often link sustainability to public service and social justice, while private universities focus on competitiveness and innovation. References to the Sustainable Development Goals (SDGs) are rare, appearing in only 2% of the statements. This suggests that sustainability integration is still nascent and needs to align more closely with the 2030 Agenda. The study concludes that there is a need to enhance coherence between stated missions and institutional practices to foster a more committed higher education system that advances sustainable development in Argentina. 2026-01-01T00:00:00Z https://hdl.handle.net/20.500.12328/5277 Management by missions: How to make the mission a part of management Cardona, Pablo; Rey, Carlos Management by Objectives has certain limitations that are not easily overcome simply by including non-financial objectives or by promoting a system of values imported from outside the management system. What is needed, therefore, is a new management system capable of enriching and making sense of the objectives. Management by Missions (MBM) rises above the limitations of MBO and, at the same time, takes into account other innovative proposals put forward in recent years such as Management by Competencies. MBM is based on the idea of distributing the corporate mission to all levels of the company, right down to the particular mission of each individual. Each mission shares in the higher-level missions, so that ultimately everyone has a stake in the corporate mission. The corporate mission is then made operational through objectives. Objectives have no value in themselves but only as a means to fulfill the mission. This new management philosophy is much richer and better able to persuade people to identify with the company they work for and so ensure superior performance at all levels of the organization. 2006-02-14T00:00:00Z https://hdl.handle.net/20.500.12328/5273 Does frequency of use enhance ChatGPT user satisfaction? The role of perceived functional capabilities and AI interaction preference Colombari, Ruggero; Marimon, Frederic; Mas-Machuca, Marta This study proposes a post-adoption socio-technical framework in which perceived functional capabilities of ChatGPT (technical dimension) and AI interaction preference (social dimension) mediate the relationship between ChatGPT usage frequency and user satisfaction. Drawing on continuance theory, expectation-confirmation theory, and socio-technical perspectives on human-technology co-adaptation, we developed a dual-mediation model and tested it using Structural Equation Modeling with data from 12,295 ChatGPT users. The results show that frequency alone is not a reliable predictor of satisfaction once social and technical mediators are considered. Specifically, satisfaction is activated through the progressive discovery of the technical tool's potential, including cognitive offloading, anthropomorphism, and other task-oriented capabilities, and through users' social preference for AI-based support over human interaction. The findings contribute to post-adoption and continuance research by offering a parsimonious socio-technical satisfaction activation model, a set of social and technical generative AI-specific activating mediators, and a perspective about the need for ad-hoc complementary technology adoption models for conversational large language model systems. As such, the study provides a foundation for future research to test, refine, and extend the proposed model across domains, as well as to enrich its technical and social constructs with additional context-specific mediators. At the practical level, the findings suggest moving beyond simply encouraging more frequent or responsible use of generative AI, and instead undertaking also complementary actions that address all the drivers of user satisfaction. This research was partially supported by project PID2024- 159200NB-I00, Generative AI in Industry: Model and Scale for Improving Quality and Productivity (GenAI-Qual), funded by MICIU/AEI/10.13039/ 501100011033 and by FEDER, EU. 2026-05-14T00:00:00Z https://hdl.handle.net/20.500.12328/5276 Meesmann Corneal Dystrophy with Epithelial Basement Membrane Abnormalities: Clinical and Genetic Analysis of Two Families with Novel and Known Mutations in KRT3 and KRT12 Charoenrook, Victor; Larena, Raquel; Ferragut Alegre, Alvaro; De Faria , Alix; Valero, Rebeca; Martí-Orpinell, Mònica; Julio, Gemma; Barraquer, Rafael I This study describes the clinical and genetic features of Meesmann epithelial corneal dystrophy (MECD) in two unrelated families and reports new genotype–phenotype associations. Ten patients from a Lebanese family (n = 4) (Family 1) and a Spanish family (n = 6) (Family 2) underwent ophthalmologic evaluation, in vivo confocal microscopy (IVCM), anterior segment optical coherence tomography (AS-OCT) with epithelial thickness mapping (ET-map), and targeted next-generation sequencing (NGS) using a custom-designed 133-gene panel associated with anterior segment dystrophies. In Family 1, a novel homozygous KRT12 c.1181T>C (p.Leu394Pro) variant was identified in the symptomatic proband and his clinically asymptomatic brother, while both parents, who were first cousins, were heterozygous for this nucleotide variant. The proband also carried the heterozygous KRT3 c.250C>T (p.Arg84Trp) variant, which has been previously reported but, to our knowledge, has not been described in co-occurrence until now. In addition, the proband showed a complex phenotype with signs of MECD and epithelial basal membrane alterations consistent with epithelial basement membrane dystrophy (EBMD). In Family 2, four affected members carried the KRT3 c.1492G>A (p.Glu498Lys) variant in heterozygosity, which has been previously described. The elderly members affected showed typical signs of MECD and EBMD. To our knowledge, these concomitant alterations have not been previously described with genetical confirmation. In conclusion, this study provides the first evidence that the co-occurrence of variants in two Meesmann corneal dystrophy-associated genes (KRT3 and KRT12) can jointly account for the disease phenotype. We also highlight the association of MECD with EBMD in both families. Characterization using IVCM and AS-OCT ET-Map provides a deeper understanding of the morphological changes and phenotypic variability in MECD, confirming the utility of this multimodal imaging approach for diagnosis and management. 2026-01-29T00:00:00Z