2026-04-17T07:57:36Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/691662025-11-21T05:31:54Zcom_2072_1057col_2072_478917col_2072_478921

urn:hdl:2445/69166 Robust and Reproducible Quantification of the Extent of Chest Radiographic Abnormalities (And It's Free!) Requena-Méndez, Ana Aldasoro, Edelweiss Muñoz, José Moore, David A. J. Tuberculosi Radiografia Programari lliure Processament d'imatges Perú Tuberculosis Radiography Open source software Image processing Peru RATIONALE: Objective, reproducible quantification of the extent of abnormalities seen on a chest radiograph would improve the user-friendliness of a previously proposed severity scoring system for pulmonary tuberculosis and could be helpful in monitoring response to therapy, including in clinical trials. METHODS: In this study we report the development and evaluation of a simple tool using free image editing software (GIMP) to accurately and reproducibly quantify the area of affected lung on the chest radiograph of tuberculosis patients. As part of a pharmacokinetic study in Lima, Peru, a chest radiograph was performed on patients with pulmonary tuberculosis and this was subsequently photographed using a digital camera. The GIMP software was used by two independent and trained readers to estimate the extent of affected lung (expressed as a percentage of total lung area) in each radiograph and the resulting radiographic SCORE. RESULTS: 56 chest radiographs were included in the reading analysis. The Intraclass correlation coefficient (ICC) between the 2 observers was 0.977 (p<0.001) for the area of lung affected and was 0.955 (p<0.001) for the final score; and the kappa coefficient of Interobserver agreement for both the area of lung affected and the score were 0.9 (p<0.001) and 0.86 (p<0.001) respectively. CONCLUSIONS: This high level of between-observer agreement suggests that this freely available software could constitute a simple and useful tool for robust evaluation of individual and serial chest radiographs. 2016-02-03T09:04:30Z 2016-02-03T09:04:30Z 2015-05-21 2016-02-02T15:33:28Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0128044 PLoS One, 2015, vol. 10, num. 5, p. e0128044 http://dx.doi.org/10.1371/journal.pone.0128044 cc by (c) Requena-Mendez et al., 2015 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Public Library of Science (PLoS) Articles publicats en revistes (ISGlobal)