2026-04-17T04:11:03Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/504672025-12-04T19:32:23Zcom_2072_1057col_2072_478908col_2072_478917col_2072_478933

00925njm 22002777a 4500 dc Aiguabella Font, Núria author Pesquer, Albert author Verdaguer i Espaulella, Xavier author Riera i Escalé, Antoni author 2014-02-20T13:16:35Z 2014-05-28T22:02:23Z 2013-05-28 2014-02-20T12:18:26Z A new approach to the synthesis of 4,5-disubstituted cyclopentenones is described. The strategy is based on the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-propargylamine as alkyne with a masked leaving group, which can be eliminated at will. This approach to the synthesis of 4,5-disubstituted cyclopentenones overcomes the problem of using the alkylation to introduce the alpha-side-chain. As an example, prostane 13-epi-12-oxo-phytodienoic acid (13-epi-12-oxo-PDA) methyl ester was synthesized. Ciclització (Química) Química biorgànica Compostos orgànics Síntesi orgànica Hormones Efecte de l'estrès sobre les plantes Estrès (Psicologia) Prostaglandines Biomolècules Ring formation (Chemistry) Bioorganic chemistry Organic compounds Organic synthesis Hormones Effect of stress on plants Stress (Psychology) Prostaglandins Biomolecules Pauson-Khand Adducts of N-Boc-propargylamine: A New Approach to 4,5-Disubstituted Cyclopentenones