2026-04-13T06:57:14Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/486952025-12-04T21:45:35Zcom_2072_1057col_2072_478917col_2072_478933

Preparation of benzolactams by Pd(II)-catalyzed carbonylation of N-unprotected arylethylamines López Barallobre, Blanca Rodríguez Ramírez, Aleix Santos, David Albert Mach, Joan Ariza Piquer, Xavier García Gómez, Jordi Granell Sanvicente, Jaime Ramón Pal·ladi (Element químic) Química organometàl·lica Reaccions químiques Lactames Imines Palladium Organometallic chemistry Chemical reactions Lactams Imines An unprecedented NH2-directed Pd(II)-catalytic carbonylation of quaternary aromatic α -amino esters to yield 6-membered 10 benzolactams has been developed. The reaction shows a strong bias to 6-membered lactams over 5-membered ones. The steric hindrance around the amino group seems to be pivotal for the success of the process. 2014-01-07T10:31:43Z 2014-01-07T10:31:43Z 2011 2014-01-07T10:31:43Z info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion 1359-7345 https://hdl.handle.net/2445/48695 580758 eng Versió postprint del document publicat a: http://dx.doi.org/10.1039/C0CC03478A Chemical Communications, 2011, vol. 47, p. 1054-1056 http://dx.doi.org/10.1039/C0CC03478A (c) López, Blanca et al., 2011 info:eu-repo/semantics/openAccess 3 p. application/pdf Royal Society of Chemistry Articles publicats en revistes (Química Inorgànica i Orgànica)