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oai:recercat.cat:2445/486302025-12-04T21:11:16Zcom_2072_1057col_2072_478781col_2072_478917col_2072_478933

Preparation of alpha-labeled aldehydes by base-catalyzed exchange reactions Ariza Piquer, Xavier Asins Muñoz, Guillermina García Gómez, Jordi García Hegardt, Fausto Makowski, Kamil Serra i Cucurull, Dolors Velasco Turbau, Javier Trastorns del metabolisme dels lípids Bioquímica Aldehids Disseny de medicaments Medicina nuclear Lipid metabolism disorders Biochemistry Aldehydes Drug design Nuclear medicine A simple, efficient protocol for the preparation of α-labeled aldehydes based on H/D exchange catalyzed by 4-(N,N-dimethylamino)pyridine or Et3N is described. High chemical yields and ratios of isotope incorporation were obtained even when small amounts (1 mmol) of aldehyde were used. 2013-12-20T11:19:18Z 2019-11-01T06:10:12Z 2010 2013-12-20T10:36:31Z info:eu-repo/semantics/article info:eu-repo/semantics/submittedVersion 0362-4803 https://hdl.handle.net/2445/48630 578380 eng Versió preprint del document publicat a: http://dx.doi.org/10.1002/jlcr.1759 Journal of Labelled Compounds and Radiopharmaceuticals, 2010, vol. 53, num. 8, p. 556-558 http://dx.doi.org/10.1002/jlcr.1759 (c) John Wiley & Sons, 2010 info:eu-repo/semantics/openAccess 6 p. application/pdf John Wiley & Sons Articles publicats en revistes (Química Inorgànica i Orgànica)