2026-04-14T02:14:06Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2285912026-04-07T22:20:28Zcom_2072_1057col_2072_478861col_2072_478916col_2072_478917

urn:hdl:2445/228591 Evaluating the quality of real-world data on adherence to oral endocrine therapy in breast cancer patients: How real-world data? Navarro i Sabaté, Àurea Font, Rebeca Espinàs Piñol, Josep Alfons Solà, Judit Martínez Soler, Fina Gil Gil, Miguel Viñas, Gemma Tibau Martorell, Ariadna Borrell, Maria Segui Palmer, Miguel Ángel Margelí Vila, Mireia Servitja, Sonia Pérez Segura, Cristina Domènech, M. Nava, Maria Ángeles Marin, Mar Gonzalez, Sergi Borràs Andrés, Josep Maria Ressenyes sistemàtiques (Investigació mèdica) Infermeria basada en l'evidència Càncer de mama Systematic reviews (Medical research) Evidence-based nursing Breast cancer Simple Summary: The objective of this study was to evaluate the validity of RWD-based adherence measurements obtained from accessible electronic health records in the Spanish national health system in all women diagnosed with breast cancer in the public healthcare system in Catalonia (Spain). Our results showed that nonadherence during the first year of treatment was around 11% in both cohorts, analysed using the RWD, and without significant differences between them. Furthermore, determinants associated with nonadherence (age and type of oral endocrine treatment) were similar in both approaches used. The results also show that it is fast and feasible to use RWD to identify individuals who are not refilling prescriptions as often as they should. In conclusion, the validity of the RWD method to estimate adherence has been confirmed and, at the same time, this method provides valuable evidence to help oncologists discuss adherence with their patients. 2026-03-30T12:13:48Z 2026-03-30T12:13:48Z 2025 2026-03-30T12:13:49Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.3390/cancers17020200 Cancers, 2025, vol. 200 https://doi.org/10.3390/cancers17020200 cc-by (c) Navarro-Sabaté, A. et al., 2025 http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess MDPI Articles publicats en revistes (Infermeria Fonamental i Clínica)