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               <dc:title>A study protocol for an experimental study for a pharmaceutical care programme to improve chronic complex disease management: PCAF programme</dc:title>
               <dc:creator>Torres-Novellas, Berta</dc:creator>
               <dc:creator>Guayta, Rafael (Guayta Escolies)</dc:creator>
               <dc:creator>Rius, Pilar</dc:creator>
               <dc:creator>Castellà, Amparo</dc:creator>
               <dc:creator>Gascón Lecha, M. Pilar</dc:creator>
               <dc:creator>Modamio Charles, Pilar</dc:creator>
               <dc:creator>Mariño Hernández, Eduardo L.</dc:creator>
               <dc:subject>Malalties cròniques</dc:subject>
               <dc:subject>Atenció farmacèutica</dc:subject>
               <dc:subject>Chronic diseases</dc:subject>
               <dc:subject>Pharmacy practice</dc:subject>
               <dc:description>The prevalence of elderly patients with chronic illnesses, associated polypharmacy and a high risk of functional and cognitive impairment has increased in recent&lt;/p>&lt;p>years. The care of Complex Chronic Patients (CCP) therefore represents a challenge for health systems in developed countries around the world. This paper presents&lt;/p>&lt;p>a study protocol that will explore the effects of an intervention within a pharmaceutical care programme (PCAF) on optimising CCP care and on the suitability of&lt;/p>&lt;p>the organisational methods proposed for the PCAF programme.&lt;/p>&lt;p>This is a multicentre experimental study. The setting will be primary health care and community pharmacies in the so-called ‘autonomous community’ of Catalonia&lt;/p>&lt;p>in Spain. The participants will be CPP attended to Primary Healthcare Centres with the CCP code in their electronic medical record. The included CCP will be&lt;/p>&lt;p>distributed in two strata depending on whether they will be considered likely to receive the arranged medicinal treatment as Monitored Dosage System according&lt;/p>&lt;p>to benefits based on criteria or not. They will then be assigned by random stratified sampling at a ratio of 1:1 to the control or intervention groups. A sample size of&lt;/p>&lt;p>860 patients is estimated. Patients will undergo 12 months follow-up. The primary outcome of this study will be the medication adherence measured by the Morisky&lt;/p>&lt;p>Green Test and the billing/prescription ratio.</dc:description>
               <dc:date>2026-01-27T10:05:55Z</dc:date>
               <dc:date>2026-01-27T10:05:55Z</dc:date>
               <dc:date>2021</dc:date>
               <dc:date>2026-01-27T10:05:55Z</dc:date>
               <dc:type>info:eu-repo/semantics/article</dc:type>
               <dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
               <dc:relation>Reproducció del document publicat a: https://doi.org/10.15761/TiM.1000262</dc:relation>
               <dc:relation>Trends in Medicine, 2021, vol. 21, p. 1-5</dc:relation>
               <dc:relation>https://doi.org/10.15761/TiM.1000262</dc:relation>
               <dc:rights>cc-by (c)  Torres-Novellas, B. et al., 2021</dc:rights>
               <dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
               <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
               <dc:publisher>Open Access Text</dc:publisher>
               <dc:source>Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)</dc:source>
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