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oai:recercat.cat:2445/2259472026-04-08T14:42:34Zcom_2072_1057col_2072_478917col_2072_478924

Sleeve gastrectomy in patients with severe obesity restores circadian rhythms and their relationship with sleep pattern Barnadas Solé, Cristina Zerón-Rugerio, María Fernanda Foncillas Corvinos, Javier Díez Noguera, Antoni Cambras Riu, Trinitat Izquierdo Pulido, Maria Obesitat Ritmes circadiaris Cirurgia Obesity Circadian rhythms Surgery Advances in research have linked alterations of circadian rhythms with obesity. However, few</p><p>studies have focused on the recovery of the circadian expression after a weight loss treatment.</p><p>Our aim was to study the alterations of the circadian rhythmicity due to morbid obesity and the</p><p>recovery of the circadian pattern after weight loss in a cohort of patients who underwent sleeve</p><p>gastrectomy. For this purpose, 41 patients with severe obesity (75% women; age [mean (SD)]</p><p>49.7 ± 10 years; BMI 44.3 ± 6.2 kg/m2) were monitored before bariatric surgery and 9 months</p><p>afterward. On both occasions, activity and wrist temperature were determined by actigraphy and</p><p>were related with weight loss. Anthropometric, biochemical, and sleep-related variables, along with</p><p>dietary intake and physical activity, were analyzed in relation with circadian rhythmicity. Results</p><p>show significant differences in the circadian expression before and after 9 months of bariatric</p><p>surgery, with more stable and less fragmented rhythms after weight loss. Moreover, only after</p><p>surgery were the circadian variables associated to sleep timing and chronotype. The findings of this</p><p>study indicate that weight loss treatment in patients with morbid obesity improves the circadian</p><p>rhythm expression, and in such a way that it could be associated with better sleep quality.</p><p>Moreover, it allows the recovery of the relationship between sleep patterns and circadian rhythm</p><p>that was lost due to the obesity. 2026-01-22T11:39:49Z 2026-01-22T11:39:49Z 2021-12-01 2026-01-22T11:39:49Z info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Versió postprint del document publicat a: https://doi.org/10.1080/07420528.2020.1866003 Chronobiology International, 2021, vol. 38, num.4, p. 565-575 https://doi.org/10.1080/07420528.2020.1866003 (c) Informa Healthcare, 2021 info:eu-repo/semantics/openAccess Informa Healthcare Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)