2026-04-17T20:14:54Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2259222026-04-07T19:02:51Zcom_2072_1057col_2072_478781col_2072_478917

Isoprenoid biosynthesis via the methylerythritol phosphate pathway: accumulation of 2-C-methyl-erythritol2,4-cyclodiphosphate in a gcpE deficient mutant of Escherichia coli Seemann, Myriam Campos Martínez, Narciso Rodríguez Concepción, Manuel Hoeffler, Jean François Grosdemange Billiard, Catherine Boronat i Margosa, Albert Rohmer, Michel Metabolisme microbià Escheríchia coli Microbial metabolism Escherichia coli In the bacterium Escherichiacoli, gcpE is an essential gene in the methylerythritol phosphate pathway for isoprenoid biosynthesis. Incubation of [1-3H]methylerythritol with an E. coli mutant defective in the gcpE gene resulted in the accumulation of [1-3H]methylerythritol 2,4-cyclodiphosphate. This suggests that the GCPE protein is involved in the further conversion of methylerythritol cyclodiphosphate into isoprenoids. 2026-01-22T07:40:14Z 2026-01-22T07:40:14Z 2002-01-28 2026-01-22T07:40:14Z info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Versió postprint del document publicat a: https://doi.org/10.1016/S0040-4039(01)02269-9 Tetrahedron Letters, 2002, vol. 43, num.5, p. 775-778 https://doi.org/10.1016/S0040-4039(01)02269-9 (c) Elsevier Ltd., 2002 info:eu-repo/semantics/openAccess Elsevier Ltd. Articles publicats en revistes (Bioquímica i Biomedicina Molecular)