2026-04-13T18:19:15Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2247702026-04-07T22:58:24Zcom_2072_1057col_2072_478798col_2072_478916col_2072_478917

Cigarettes vs. e-cigarettes: Passive exposure at home measured by means of airborne marker and biomarkers Ballbè i Gibernau, Montse Martínez Sánchez, José M. Sureda, Xisca Fu Balboa, Marcela Pérez Ortuño, Raúl Pascual, José A. Saltó, Esteve Fernández Muñoz, Esteve Marcadors bioquímics Alcaloides Cigars Biochemical markers Alkaloids Cigars Background: There is scarce evidence about passive exposure to the vapour released or exhaled from electronic cigarettes (e-cigarettes) under real conditions. The aim of this study is to characterise passive exposure to nicotine from e-cigarettes' vapour and conventional cigarettes' smoke at home among non-smokers under real-use conditions. Methods: We conducted an observational study with 54 non-smoker volunteers from different homes: 25 living at home with conventional smokers, 5 living with nicotine e-cigarette users, and 24 from control homes (not using conventional cigarettes neither e-cigarettes). We measured airborne nicotine at home and biomarkers (cotinine in saliva and urine). We calculated geometric mean (GM) and geometric standard deviations (GSD). We also performed ANOVA and Student's t tests for the log-transformed data. We used Bonferroni-corrected t-tests to control the family error rate for multiple comparisons at 5%. Results: The GMs of airborne nicotine were 0.74 μg/m(3) (GSD=4.05) in the smokers' homes, 0.13 μg/m(3) (GSD=2.4) in the e-cigarettes users' homes, and 0.02 μg/m(3) (GSD=3.51) in the control homes. The GMs of salivary cotinine were 0.38 ng/ml (GSD=2.34) in the smokers' homes, 0.19 ng/ml (GSD=2.17) in the e-cigarettes users' homes, and 0.07 ng/ml (GSD=1.79) in the control homes. Salivary cotinine concentrations of the non-smokers exposed to e-cigarette's vapour at home (all exposed ≥ 2 h/day) were statistically significant different that those found in non-smokers exposed to second-hand smoke ≥ 2 h/day and in non-smokers from control homes. Conclusions: The airborne markers were statistically higher in conventional cigarette homes than in e-cigarettes homes (5.7 times higher). However, concentrations of both biomarkers among non-smokers exposed to conventional cigarettes and e-cigarettes' vapour were statistically similar (only 2 and 1.4 times higher, respectively). The levels of airborne nicotine and cotinine concentrations in the homes with e-cigarette users were higher than control homes (differences statistically significant). Our results show that non-smokers passively exposed to e-cigarettes absorb nicotine. 2025-12-09T17:29:03Z 2025-12-09T17:29:03Z 2014-09-27 2025-12-09T17:29:04Z info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion 0013-9351 https://hdl.handle.net/2445/224770 651754 25262078 eng Versió postprint del document publicat a: https://doi.org/10.1016/j.envres.2014.09.005 Environmental Research, 2014, vol. 135, p. 76-80 https://doi.org/10.1016/j.envres.2014.09.005 (c) Academic Press, 2014 info:eu-repo/semantics/openAccess 16 p. application/pdf Elsevier Articles publicats en revistes (Ciències Clíniques)