2026-04-18T04:27:24Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2227742026-04-07T23:31:30Zcom_2072_1057col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Pérez Sáez, María José author Melilli, Edoardo author Arias, Marta author Franco, Antonio author Martínez, Rocío author Sancho, Asunción author Molina, María author Facundo, Carme author Polanco, Natalia author López, Verónica author Mazuecos, Auxiliadora author Cabello, Sheila author González García, María Elena author Suárez, María Luisa author Auyanet, Ingrid author Espi, Jordi author García Falcón, Teresa author Ruiz, Juan Carlos author Galeano, Cristina author Artamendi, Marta author Rodríguez Ferrero, María Luisa author Portolés, José author Santana, María Auxiliadora author Martín Moreno, Paloma Leticia author Arhda, Nisrine author Calvo, Marta author Mendiluce, Alicia author Macía, Manuel author Pérez Tamajón, María Lourdes author Teresa, Javier de author Gascó, Blanca author Soriano, Sagrario author Tabernero, Guadalupe author Vara, Lourdes de la author Ramos, Ana María author Martínez, Rafael author Montero de Espinosa, Enrique author Zalve, José Luis author Pascual, Julio (Pascual Santos) author Rodríguez Mañas, Leocadio author Gutiérrez Dalmau, Alex author Moreso, Francesc author 2025-08-26T11:54:51Z 2025-08-26T11:54:51Z 2025-06-24 2025-08-19T08:09:07Z Frailty is a frequent condition among kidney transplant candidates (KTc) that confers poor outcomes after transplantation. We aimed to establish frailty prevalence in a representative sample of KTc in Spain. We conducted a multicenter cross-sectional study including 1194 KTc >= 50 years. Frailty was assessed by the FRAIL scale. Mean age was 64.2 years; 38.4% were female. Median Charlson comorbidity index (CCI) was 6 [4-7] and the total number of medications was 9 [7-12]. We found that 8.2% of patients were frail and 41.5% were pre-frail. Frailty was more frequent among females (60.2% of frail vs. 32.8% of robust; p < 0.001), hemodialysis patients (74.5% of frail vs. 67.1% of robust; p = 0.02), and those with a high burden of disease (54.6% of frail patients with CCI >6 vs. 29.3% of robust; p < 0.001). The multivariable analysis confirmed that frailty was associated with the female sex (OR 3.9 [2.5-6.2]); higher CCI (>6 OR 2.9 [1.6-54]); and the number of medications (OR -per medication- 1.13 [1.07-1.2]). Almost 50% of KTc in Spain are pre-frail or frail. Frailty is more prevalent between women and patients with high comorbidity burden. Identifying those candidates at risk is essential to establish risks and implement strategies to minimize them. Malalties del ronyó Trasplantament renal Kidney diseases Kidney transplantation Frailty Prevalence and Characterization Among Kidney Transplant Candidates in Spain: A Multicenter Study