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00925njm 22002777a 4500 dc Alemany, Marià, 1946- author 2012-02-24T09:59:55Z 2012-02-24T09:59:55Z 2011 Obesity, the excessive accumulation of body fat, is a main defining feature of the metabolic syndrome, and overweight is often an early indication of the future severity and development of associated pathologies. There is a graded relationship between the increase in body adipose tissue content and the severity of insulin resistance, hypertension, and altered blood lipids, in addition to a number of additional disturbances in energy, nitrogen, and xenobiotic metabolism. Obesitat Metabolisme Obesity Metabolism The defense of adipose tissue against excess substrate-induced hyperthrophia: Immune system cell infiltration and arrested metabolic activity