2026-04-14T03:49:06Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2166212025-12-05T13:04:42Zcom_2072_1057col_2072_478798col_2072_478916col_2072_478917col_2072_478932

00925njm 22002777a 4500 dc Kiebs, Maximillian author Farrar, Danielle C. author Yrondi, Antoine author Cardoner, N. (Narcís) author Tuovinen, Noora author Redlich, Ronny author Dannlowski, Udo author Soriano Mas, Carles author Dols, Annemiek author Takamiya, Akihiro author Tendolkar, Indira author Narr, Katherine L. author Espinoza, Randall author Laroy, Maarten author Eijndhoven, Philip van author Verwijk, Esmée author Waarde, Jeroen van author Verdijk, Joey author Maier, Hannah B. author Nordanskog, Pia author Wingen, Guido van author Diermen, Linda van author Emsell, Louise author Bouckaert, Filip author Repple, Jonathan author Camprodon, Joan A. author Wade, Benjamin S. C. author Donaldson, K. Tristan author Oltedal, Leif author Kessler, Ute author Hammar, Åsa author Sienaert, Pascal author Hebbrecht, Kaat author Urretavizcaya Sarachaga, Mikel author Belge, Jean-Baptiste author Argyelan, Miklos author Baradits, Mate author Obbels, Jasmien author Draganski, Bogdan author Philipsen, Alexandra author Sartorius, Alexander author Rhebergen, Didericke author Ousdal, Olga Therese author Hurlemann, René author McClintock, Shawn author Erhardt, Erik B. author Abbott, Christopher author 2024-11-19T17:11:09Z 2024-11-19T17:11:09Z 2024-11-01 2024-11-19T17:11:10Z The Global ECT MRI Research Collaboration (GEMRIC) has collected clinical and neuroimaging data of patients treated with electroconvulsive therapy (ECT) from around the world. Results to date have focused on neuroimaging correlates of antidepressant response. GEMRIC sites have also collected longitudinal cognitive data. Here, we summarize the existing GEMRIC cognitive data and provide recommendations for prospective data collection for future ECT-imaging investigations. We describe the criteria for selection of cognitive measures for mega-analyses: Trail Making Test Parts A (TMT-A) and B (TMT-B), verbal fluency category (VFC), verbal fluency letter (VFL), and percent retention from verbal learning and memory tests. We performed longitudinal data analysis focused on the pre-/post ECT assessments with healthy comparison (HC) subjects at similar timepoints and assessed associations between demographic and ECT parameters with cognitive changes. The study found an interaction between electrode placement and treatment number for VFC (F(1,107) = 4.14, p = 0.04). Higher treatment was associated with decreased VFC performance with right unilateral electrode placement. Percent retention showed a main effect for group, with post-hoc analysis indicating decreased cognitive performance among the HC group. However, there were no significant effects of group or group interactions observed for TMT-A, TMT-B, or VFL. We assessed the current GEMRIC cognitive data and acknowledge the limitations associated with this data set including the limited number of neuropsychological domains assessed. Aside from the VFC and treatment number relationship, we did not observe ECT-mediated neurocognitive effects in this investigation. We provide prospective cognitive recommendations for future ECT-imaging investigations focused on strong psychometrics and minimal burden to subjects. Cognició Electroteràpia Depressió psíquica Neuropsicologia Cognition Electrotherapeutics Mental depression Neuropsychology Electroconvulsive therapy and cognitive performance from the Global ECT MRI Research Collaboration