2026-04-17T20:00:39Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2163972025-11-20T15:09:49Zcom_2072_1057col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Ferreres Riera, Jose Ramon author Molinero Caturla, J. author Sánchez Sánchez, J. author Gamissans, M. author Vinyals, A. author Bermejo, J. author Penín, R. M. author Fabra, À. author Marcoval Caus, Joaquim author 2024-11-12T12:34:54Z 2024-11-12T12:34:54Z 2024-10-01 2024-11-05T11:26:54Z Background: The location of cutaneous melanoma is associated with photoexposure. Objectives: To retrospectively analyze changes in the location of cutaneous melanoma over the past 30 years. Patients and methods: All patients treated at our hospital for cutaneous melanoma from 1988 through 2017 were prospectively collected. Data obtained in cases diagnosed from 1988 through June 2006 were compared to those diagnosed from July 2006 through 2017. Results: A total of 1,937 patients (876 men and 1061 women; median age, 57 years; interquartile range 27) were diagnosed with primary cutaneous melanoma. The location of melanoma was head and neck (470 cases), trunk (745 cases), upper limbs (239 cases), and lower limbs (483 cases). From July 2006 through 2017 we detected an increase in the incidence of head and neck melanomas (19.9% vs 28.6%, p < 0.001). A drop in the incidence of melanomas located in the lower extremities was also seen in women (39.8% vs 30.4%, p < 0.001), and in the trunk men (57.5% vs 47.3%, p = 0.003). In the multivariate analyses, only the decrease in melanomas located in lower extremities in women remained significant. Conclusion: The increased incidence of head and neck melanomas in both sexes and the decrease in trunk melanomas in men can be attributed to the aging of our population. The reduction in the incidence of melanomas in the lower extremities in women could be associated with changes in photoexposure patterns. Analyzing the factors possibly associated with these changes would contribute to better understanding the pathogenesis of cutaneous melanoma for prevention purposes. (c) 2024 AEDV. Published by Elsevier Espa & ntilde;a, S.L.U. Melanoma Radiació ultraviolada Melanoma Ultraviolet radiation Cambios en la localización del melanoma cutáneo en los últimos 30 años. Estudio observacional retrospectivo