2026-04-13T07:16:21Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2157622025-12-05T12:37:29Zcom_2072_1057col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Buades, Juan Manuel author Figueras Nart, Ignasi author Goicoechea, Marian author Sánchez Villanueva, Rafael Jesús author Serra Baldrich, Esther author 2024-10-14T13:46:33Z 2024-10-14T13:46:33Z 2024-07-01 2024-10-01T11:41:51Z Chronic kidney disease-associated pruritus (CKD-aP) is one of the most common and disabling comorbidities in patients with advanced CKD. In addition, it is associated with an increased risk of mortality, poorer quality of life, sleep disorders, mental health disorders, and increased use of health care resources. The clinical presentation of CKD-aP is very heterogeneous, making it difficult to diagnose and treat. Currently, there are no national guidelines on the management of CKD-aP. The aim of this document is to provide national consensus recommendations for the diagnostic and therapeutic management of CKD-aP. The document was prepared in three phases: a diagnostic and therapeutic management algorithm was proposed by a small group of nephrology specialists; the proposal was validated by a larger group of nephrologists; and a second validation by a multidisciplinary group that also included dermatology specialists. The diagnostic and therapeutic management algorithm attempts to cover the current need of a lack of specific guidelines for the adequate management of CKD-aP. At the same time, it introduces the use of difelikefalin, the first and only drug specifically approved for CKD-aP, with a good safety and efficacy profile. (c) 2023 Published by Elsevier Espa na, a, S.L.U. on behalf of Sociedad Espa nola ola de Nefrolog & imath;a. This is an open access article under the CC BY-NC-ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/). Pruïja Insuficiència renal crònica Itching Chronic renal failure Documento de información y consenso para el manejo diagnóstico y terapéutico del prurito asociado a la enfermedad renal crónica en pacientes en hemodiálisis en España