2026-04-17T05:37:42Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2148712025-12-05T12:16:25Zcom_2072_1057col_2072_478916col_2072_478917

Real Implication of Fertility-Sparing Surgery for Ovarian Cancer: Reproductive Outcomes Heras, Marta Alonso Espias, Maria Arencibia, Octavio Minig, Lucas Martí, Lola Diestro, Maria Dolores Cespedes, Juan Níguez, Isabel Gil Ibáñez, Blanca Díaz Feijoo, Berta Llueca, Antoni Rosado, Claudia Iacoponi, Sara Lopez de la Manzanara, Carlos Morales, Sara Fernández Galguera, María José Cano, Ana Gorostidi, Mikel Zapardiel, Ignacio Càncer d'ovari Fecunditat Ovarian cancer Fertility Background: to prove the effectivity of fertility-sparing procedures in early-stage ovarian cancer by assessing pregnancy rates and obstetrical outcomes. Methods: we performed a retrospective multicenter study among 55 Spanish hospitals, collecting patients from 18 to 40 years old with diagnosis of early-stage ovarian cancer, epithelial (EOC) or non-epithelial (non-EOC), from January 2010 to December 2019. Data on the use of assisted reproductive techniques, pregnancy attempts and obstetrical outcomes were collected. Results: a total of 150 patients met inclusion criteria, 70 (46.6%) EOC and 80 (53.4%) non-EOC. Pregnancy attempts were reported in 51 (34%) patients, with 42 (28%) patients carrying the pregnancy to term. Among them, 30 (71.4%) underwent surgery alone and 12 (28.6%) had additional postoperative chemotherapy. A total of 32 (76.1% patients) had spontaneous pregnancies and 10 (23.9%) required in vitro fertilization. There was only one (2.4%) complication reported. Vaginal delivery was reported in twenty-nine (69%) patients and cesarean section in five (11.9%) patients. Conclusions: fertility-sparing management for ovarian cancer seems to be an option with proven good pregnancy rates and low complications. The selection of patients must consider strict criteria in order to maintain a good prognosis. 2024-08-29T12:22:32Z 2024-08-29T12:22:32Z 2024-07-03 2024-07-31T10:32:44Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2075-4418 https://hdl.handle.net/2445/214871 39001314 eng Reproducció del document publicat a: https://doi.org/10.3390/diagnostics14131424 Diagnostics, 2024, vol. 14, num. 13 https://doi.org/10.3390/diagnostics14131424 cc by (c) Heras, Marta et al, 2024 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess 10 p. application/pdf MDPI AG Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))