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Neurovascular unit on a chip: the relevance and maturity as an advanced in vitro model Palma Florez, Sujey Lagunas Targarona, Anna Mir Llorente, Mònica Malalties cerebrovasculars Assistència hospitalària Cerebrovascular disease Hospital care The brain is a high-energy demanding organ, consuming around 20% of the metabolic energy generated. To fulfill this demand, cerebral blood flow (CBF) supplies oxygen and glucose continuously through the intricate network of cerebral blood vessels. Although for many years brain activity and blood flow were conceived as independent processes, MRI-based functional brain imaging demonstrated that there is a coupling between them, leading to the concept of the neurovascular unit (NVU) to reflect their interplay (Raichle and Mintun, 2006). 2024-07-10T09:55:45Z 2024-07-10T09:55:45Z 2024-06-24 2024-07-08T08:33:44Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.4103/1673-5374.385863 Neural Regeneration Research, 2024, vol. 19, num. 6, p. 1165-1166 https://doi.org/10.4103/1673-5374.385863 cc by (c) Palma Florez, Sujey et al, 2024 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Wolters Kluwer Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))