2026-04-13T07:00:05Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2062302025-12-04T19:14:16Zcom_2072_1057col_2072_478858col_2072_478917

00925njm 22002777a 4500 dc Mont Girbau, Lluís author Roca Luque, Ivo author Althoff, Till F. author 2024-01-24T13:29:13Z 2024-01-24T13:29:13Z 2021-12-11 2023-07-06T12:58:41Z Late gadolinium enhancement (LGE) MRI is capable of detecting not only native cardiac fibrosis, but also ablation-induced scarring. Thus, it offers the unique opportunity to assess ablation lesions non-invasively. In the atrium, LGE-MRI has been shown to accurately detect and localise gaps in ablation lines. With a negative predictive value close to 100% it can reliably rule out pulmonary vein reconnection non-invasively and thus may avoid unnecessary invasive repeat procedures where a pulmonary vein isolation only approach is pursued. Even LGE-MRI-guided repeat pulmonary vein isolation has been demonstrated to be feasible as a standalone approach. LGE-MRI-based lesion assessment may also be of value to evaluate the efficacy of ventricular ablation. In this respect, the elimination of LGE-MRI-detected arrhythmogenic substrate may serve as a potential endpoint, but validation in clinical studies is lacking. Despite holding great promise, the widespread use of LGE-MRI is still limited by the absence of standardised protocols for image acquisition and post-processing. In particular, reproducibility across different centres is impeded by inconsistent thresholds and internal references to define fibrosis. Thus, uniform methodological and analytical standards are warranted to foster a broader implementation in clinical practice. Malalties cardiovasculars Ressonància magnètica Cardiovascular diseases Magnetic resonance Ablation Lesion Assessment with MRI