2026-04-13T01:41:42Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/2062302025-12-04T19:14:16Zcom_2072_1057col_2072_478858col_2072_478917

urn:hdl:2445/206230 Ablation Lesion Assessment with MRI Mont Girbau, Lluís Roca Luque, Ivo Althoff, Till F. Malalties cardiovasculars Ressonància magnètica Cardiovascular diseases Magnetic resonance Late gadolinium enhancement (LGE) MRI is capable of detecting not only native cardiac fibrosis, but also ablation-induced scarring. Thus, it offers the unique opportunity to assess ablation lesions non-invasively. In the atrium, LGE-MRI has been shown to accurately detect and localise gaps in ablation lines. With a negative predictive value close to 100% it can reliably rule out pulmonary vein reconnection non-invasively and thus may avoid unnecessary invasive repeat procedures where a pulmonary vein isolation only approach is pursued. Even LGE-MRI-guided repeat pulmonary vein isolation has been demonstrated to be feasible as a standalone approach. LGE-MRI-based lesion assessment may also be of value to evaluate the efficacy of ventricular ablation. In this respect, the elimination of LGE-MRI-detected arrhythmogenic substrate may serve as a potential endpoint, but validation in clinical studies is lacking. Despite holding great promise, the widespread use of LGE-MRI is still limited by the absence of standardised protocols for image acquisition and post-processing. In particular, reproducibility across different centres is impeded by inconsistent thresholds and internal references to define fibrosis. Thus, uniform methodological and analytical standards are warranted to foster a broader implementation in clinical practice. 2024-01-24T13:29:13Z 2024-01-24T13:29:13Z 2021-12-11 2023-07-06T12:58:41Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.15420/aer.2021.63 Arrhythm Electrophysiol Rev, 2022, vol. 11, num. 1 https://doi.org/10.15420/aer.2021.63 cc by (c) Mont Girbau, Lluís et al., 2021 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Radcliff Cardiology Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)