<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-04-13T06:37:29Z</responseDate><request verb="GetRecord" identifier="oai:www.recercat.cat:2445/197756" metadataPrefix="mets">https://recercat.cat/oai/request</request><GetRecord><record><header><identifier>oai:recercat.cat:2445/197756</identifier><datestamp>2025-12-05T04:20:51Z</datestamp><setSpec>com_2072_1057</setSpec><setSpec>col_2072_478809</setSpec><setSpec>col_2072_478917</setSpec></header><metadata><mets xmlns="http://www.loc.gov/METS/" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" ID="&#xa;&#x9;&#x9;&#x9;&#x9;DSpace_ITEM_2445-197756" TYPE="DSpace ITEM" PROFILE="DSpace METS SIP Profile 1.0" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd" OBJID="&#xa;&#x9;&#x9;&#x9;&#x9;hdl:2445/197756">
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                  <mods:namePart>Darbà, Josep</mods:namePart>
               </mods:name>
               <mods:name>
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                     <mods:roleTerm type="text">author</mods:roleTerm>
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                  <mods:namePart>Ascanio, Meritxell</mods:namePart>
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                  <mods:dateIssued encoding="iso8601">2023-05-09T16:33:51Z2023-05-09T16:33:51Z2023-02-272023-05-09T16:33:51Z</mods:dateIssued>
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               <mods:abstract>Objective:This study aimed to assess the comorbidity profile, use of health care resources and med-ical costs of patients with chronic obstructive pulmonary disease (COPD) treated at the hospital levelin Spain.Methods:Admission records of patients with COPD and at least two admissions registered betweenJanuary 2016 and December 2020 were obtained from a Spanish hospital discharge database and ana-lyzed in a retrospective multicenter study.Results:95,140 patients met the inclusion criteria; 69.1% were males with a median age of 75years.Mean Charlson comorbidity index (CCI) was 1.9 in the index admission, increasing to 2.1 during thefollow-up period. An acute exacerbation of COPD was registered in 93.6% of patients in the indexadmission; other secondary diagnoses included respiratory failure (56.8%), essential hypertension(36.9%), hypercholesterolemia (26.7%) and diabetes (26.3%). The age-adjusted incidence rate of COPDwas 22.6 per 10,000 persons over the study period, decreasing significantly in the year 2020. Mortalityrate was 4.1% for COPD patients, increasing to 6.6% in the year 2020. The year 2020, 191 patients reg-istered a COVID-19 infection, with a mortality rate of 23.0%. Length of hospital stay, and intensive careunit (ICU) stay increased in the follow-up period versus the index admission, similar to admission costs.Mean admission cost wase3212 in the index admission, with cost increases being associated withage, length of stay, ICU stay and CCI.Conclusions:Patients'condition worsened significantly over the follow-up period, in terms of comor-bidity and dependence on respirator, with an increased mortality rate and higher admission costs.</mods:abstract>
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               <mods:accessCondition type="useAndReproduction">cc by-nc-nd (c) Darbà et al., 2023 http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess</mods:accessCondition>
               <mods:subject>
                  <mods:topic>Malalties de l'aparell respiratori</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Economia de la salut</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Hospitals</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Espanya</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Respiratory diseases</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Medical economics</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Hospitals</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Spain</mods:topic>
               </mods:subject>
               <mods:titleInfo>
                  <mods:title>Incidence and medical costs of chronic obstructive respiratory disease in Spanish hospitals: a retrospective database analysis</mods:title>
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               <mods:genre>info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion</mods:genre>
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