2026-04-17T15:00:58Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1912602025-12-05T14:10:34Zcom_2072_1057col_2072_478815col_2072_478917

The burden of perioperative hypertension/hypotension: A systematic review Lizano Díez, Irene Poteet, Stephen Burniol-Garcia, Adrià Cerezales, Mónica Hipertensió Cirurgia Hypertension Surgery Study objective: Our goal is to review the outcomes of acute hypertensive/hypotensive episodes from articles published in the past 10 years that assessed the short- and long-term impact of acute hypertensive/hypotensive episodes in the perioperative setting. Methods: We conducted a systematic peer review based upon PROSPERO and Cochrane Handbook protocols. The following study characteristics were collected: study type, author, year, population, sample size, their definition of acute hypertension, hypotension or other measures, and outcomes (probabilities, odds ratio, hazard ratio, and relative risk) and the p-values; and they were classified according to the type of surgery (cardiac and non-cardiac). Results: A total of 3,680 articles were identified, and 66 articles fulfilled the criteria for data extraction. For the perioperative setting, the number of articles varies by outcome: 20 mortality, 16 renal outcomes, 6 stroke, 7 delirium and 34 other outcomes. Hypotension was reported to be associated with mortality (OR 1.02-20.826) as well as changes from the patient's baseline blood pressure (BP) (OR 1.02-1.36); hypotension also had a role in the development of acute kidney injury (AKI) (OR 1.03-14.11). Postsurgical delirium was found in relation with BP lability (OR 1.018-1.038) and intra- and postsurgical hypotension (OR 1.05-1.22), and hypertension (OR 1.44-2.34). Increased OR (37.67) of intracranial hemorrhage was associated to postsurgical systolic BP >130 mmHg. There was a wide range of additional diverse outcomes related to hypo-, hypertension and BP lability. Conclusions: The perioperative management of BP influences short- and long-term effects of surgical procedures in cardiac and non-cardiac interventions; these findings support the burden of BP fluctuations in this setting. 2022-11-29T08:35:45Z 2022-11-29T08:35:45Z 2022-02-01 2022-11-29T08:35:45Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 1932-6203 https://hdl.handle.net/2445/191260 720580 eng Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0263737 PLoS One, 2022 https://doi.org/10.1371/journal.pone.0263737 cc-by (c) Lizano Díez, Irene et al., 2022 https://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess application/pdf Public Library of Science (PLoS) Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)