2026-04-14T02:41:49Zhttps://recercat.cat/oai/request
oai:recercat.cat:2445/1895642025-11-20T15:01:24Zcom_2072_1057col_2072_478916col_2072_478917
RECERCAT author Llaha, Fjorida author Cayssials, Valerie author Farràs, Marta author Agudo, Antonio author Sandström, Maria author Eriksen, Anne Kirstine author Tjønneland, Anne author Boutron-Ruault, Marie-Christine author Laouali, Nasser author Truong, Thérèse author Le Cornet, Charlotte author Katzke, Verena author Schulze, Matthias B. author Palli, Domenico author Krogh, Vittorio author Signoriello, Simona author Tumino, Rosario author Ricceri, Fulvio author Skeie, Guri author Jensen, Torill Miriam Enget author Chen, Sairah Lai Fa author Lasheras, Cristina author Rodriguez Barranco, Miguel author Amiano, Pilar author Huerta, José María author Guevara, Marcela author Almquist, Martin author Nilson, Lena Maria author Hennings, Joakim author Papier, Keren author Heath, Alicia K. author Weiderpass, Elisabete author Rinaldi, Sabina author Zamora-Ros, Raul 2022-10-03T09:56:57Z2022-10-03T09:56:57Z2022-09-022022-09-29T10:22:47Z BackgroundThe Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. MethodsOver 450,000 men and women from nine European countries were followed up for a mean of 14.1 years, during which 712 differentiated TC cases were identified. Adherence to MD was estimated using the relative MD (rMED) score, an 18-point scale including alcohol, and the adapted rMED (arMED) score, a 16-point scale excluding alcohol. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression models adjusted for potential confounding factors. ResultsAdherence to the arMED score was not associated with the risk of differentiated TC (HRhigh vs. low adherence = 0.94, 95% CI: 0.70-1.25; p-trend 0.27), while a suggestive, but non-statistically significant inverse relationship was observed with rMED (HRhigh vs. low adherence = 0.88, 95% CI: 0.68-1.14; p-trend 0.17). Low meat (HRlow vs. high meat intake = 0.81, 95% CI: 0.67-0.99; p-trend = 0.04) and moderate alcohol (HRmoderate vs. non-moderate intake = 0.88, 95% CI: 0.75-1.03) intake were related with lower differentiated TC risk. ConclusionsOur study shows that a high adherence to MD is not strongly related to differentiated TC risk, although further research is required to confirm the impact of MD and, especially, meat intake in TC risk. cc by (c) Llaha, Fjorida et al., 2022 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Cuina mediterrània Càncer de tiroide Mediterranean cooking Thyroid gland cancer Adherence to mediterranean diet and the risk of differentiated thyroid cancer in a European cohort: The EPIC study info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion