2026-04-14T02:34:40Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1895642025-11-20T15:01:24Zcom_2072_1057col_2072_478916col_2072_478917

urn:hdl:2445/189564 Adherence to mediterranean diet and the risk of differentiated thyroid cancer in a European cohort: The EPIC study Llaha, Fjorida Cayssials, Valerie Farràs, Marta Agudo, Antonio Sandström, Maria Eriksen, Anne Kirstine Tjønneland, Anne Boutron-Ruault, Marie-Christine Laouali, Nasser Truong, Thérèse Le Cornet, Charlotte Katzke, Verena Schulze, Matthias B. Palli, Domenico Krogh, Vittorio Signoriello, Simona Tumino, Rosario Ricceri, Fulvio Skeie, Guri Jensen, Torill Miriam Enget Chen, Sairah Lai Fa Lasheras, Cristina Rodriguez Barranco, Miguel Amiano, Pilar Huerta, José María Guevara, Marcela Almquist, Martin Nilson, Lena Maria Hennings, Joakim Papier, Keren Heath, Alicia K. Weiderpass, Elisabete Rinaldi, Sabina Zamora-Ros, Raul Cuina mediterrània Càncer de tiroide Mediterranean cooking Thyroid gland cancer BackgroundThe Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. MethodsOver 450,000 men and women from nine European countries were followed up for a mean of 14.1 years, during which 712 differentiated TC cases were identified. Adherence to MD was estimated using the relative MD (rMED) score, an 18-point scale including alcohol, and the adapted rMED (arMED) score, a 16-point scale excluding alcohol. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression models adjusted for potential confounding factors. ResultsAdherence to the arMED score was not associated with the risk of differentiated TC (HRhigh vs. low adherence = 0.94, 95% CI: 0.70-1.25; p-trend 0.27), while a suggestive, but non-statistically significant inverse relationship was observed with rMED (HRhigh vs. low adherence = 0.88, 95% CI: 0.68-1.14; p-trend 0.17). Low meat (HRlow vs. high meat intake = 0.81, 95% CI: 0.67-0.99; p-trend = 0.04) and moderate alcohol (HRmoderate vs. non-moderate intake = 0.88, 95% CI: 0.75-1.03) intake were related with lower differentiated TC risk. ConclusionsOur study shows that a high adherence to MD is not strongly related to differentiated TC risk, although further research is required to confirm the impact of MD and, especially, meat intake in TC risk. 2022-10-03T09:56:57Z 2022-10-03T09:56:57Z 2022-09-02 2022-09-29T10:22:47Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Reproducció del document publicat a: https://doi.org/10.3389/fnut.2022.982369 Frontiers in Nutrition, 2022, vol. 9 https://doi.org/10.3389/fnut.2022.982369 cc by (c) Llaha, Fjorida et al., 2022 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Frontiers Media SA Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))