2026-04-17T03:15:55Zhttps://recercat.cat/oai/requestoai:recercat.cat:2445/1861502025-11-20T14:56:39Zcom_2072_1057col_2072_478916col_2072_478917
RECERCAT
author
Casamitjana, Joan
author
Espinet, Elisa
author
Rovira, Meritxell
2022-06-01T13:51:39Z2022-06-01T13:51:39Z2022-05-032022-06-01T06:54:30Z
In recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable models for regenerative medicine in diabetes and to accurately study PDAC biology and treatment response are essential in the pancreatic field. Pancreatic organoids can be generated from healthy pancreas or pancreatic tumors and constitute an important translational bridge between in vitro and in vivo models. Here, we review the rapidly emerging field of pancreatic organoids and summarize the current applications of the technology to tissue regeneration, disease modelling, and drug screening.
cc by (c) Casamitjana, Joan et al, 2022 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess
Malalties del pàncrees
Medicina regenerativa
Pancréas diseases
Regenerative medicine
Pancreatic Organoids for Regenerative Medicine and Cancer Research
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion