2026-04-13T01:12:04Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1861502025-11-20T14:56:39Zcom_2072_1057col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc Casamitjana, Joan author Espinet, Elisa author Rovira, Meritxell author 2022-06-01T13:51:39Z 2022-06-01T13:51:39Z 2022-05-03 2022-06-01T06:54:30Z In recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable models for regenerative medicine in diabetes and to accurately study PDAC biology and treatment response are essential in the pancreatic field. Pancreatic organoids can be generated from healthy pancreas or pancreatic tumors and constitute an important translational bridge between in vitro and in vivo models. Here, we review the rapidly emerging field of pancreatic organoids and summarize the current applications of the technology to tissue regeneration, disease modelling, and drug screening. Malalties del pàncrees Medicina regenerativa Pancréas diseases Regenerative medicine Pancreatic Organoids for Regenerative Medicine and Cancer Research