2026-04-13T02:28:59Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1855902025-11-19T21:44:12Zcom_2072_1057col_2072_478825col_2072_478917

00925njm 22002777a 4500 dc Cendra Gascón, María del Mar author Torrents Serra, Eduard author 2022-05-16T14:38:32Z 2022-05-16T14:38:32Z 2021-08-01 2022-05-16T14:38:32Z Pseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact with a broad range of microorganisms have a substantial clinical impact. This review focuses on the main traits of P. aeruginosa biofilms, such as the structural composition and regulatory networks involved, placing particular emphasis on the clinical challenges they represent in terms of antimicrobial susceptibility and biofilm infection clearance. Furthermore, the ability of P. aeruginosa to grow together with other microorganisms is a significant pathogenic attribute with clinical relevance; hence, the main microbial interactions of Pseudomonas are especially highlighted and detailed throughout this review. This article also explores the infections caused by single and polymicrobial biofilms of P. aeruginosa and the current models used to recreate them under laboratory conditions. Finally, the antimicrobial and antibiofilm strategies developed against P. aeruginosa mono and multispecies biofilms are detailed at the end of this review Biofilms Bacteris gramnegatius Biofilms Gram-negative bacteria Pseudomonas aeruginosa's biofilms and their partners in crime