2026-04-13T01:55:44Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1840582025-12-05T13:11:29Zcom_2072_1057col_2072_478798col_2072_478858col_2072_478916col_2072_478917col_2072_478921

00925njm 22002777a 4500 dc Nishi, Stephanie K. author Babio, Nancy author Gómez Martínez, Carlos author Martínez-González, Miguel Ángel, 1957- author Ros Rahola, Emilio author Corella Piquer, Dolores author Castañer, Olga author Martínez, J. Alfredo, 1957- author Alonso Gómez, Ángel M. author Wärnberg, Julia author Vioque, Jesús author Romaguera, Dora author López Miranda, José author Estruch Riba, Ramon author Tinahones, Francisco J. author Lapetra, José author Serra Majem, Lluís author Bueno Cavanillas, Aurora author Tur, Josep A. author Martín Sánchez, Vicente author Pintó Sala, Xavier author Delgado Rodríguez, Miguel author Matía Martín, Pilar author Vidal i Cortada, Josep author Vázquez, Clotilde author Daimiel, Lidia author Razquin, Cristina author Coltell, Óscar author Becerra Tomás, Nerea author Torre Fornell, Rafael de la author Abete, Itziar author Sorto Sanchez, Carolina author Barón López, Francisco Javier author Signes Pastor, Antonio J. author Konieczna, Jadwiga author García Ríos, Antonio author Casas Rodríguez, Rosa M. author Gomez Perez, Ana Maria author Santos Lozano, José Manuel author García Arellano, Ana author Guillem Saiz, Patricia author Ni, Jiaqi author Soria Florido, María Trinidad author Zulet, M. Angeles author Vaquero Luna, Jessica author Toledo Atucha, Estefanía author Fitó Colomer, Montserrat author Salas Salvadó, Jordi author 2022-03-15T09:05:32Z 2022-03-15T09:05:32Z 2021-12-13 2022-03-15T09:05:32Z Background and Aims: Plant-forward dietary patterns have been associated with cardiometabolic health benefits, which, in turn, have been related to cognitive performance with inconsistent findings. The objective of this study was to examine the relationship between baseline adherence to three a priori dietary patterns (Mediterranean, DASH, and MIND diets) with 2-year changes in cognitive performance in older adults with overweight or obesity and high cardiovascular disease risk. Methods: A prospective cohort analysis was conducted within the PREDIMED-Plus trial, involving 6,647 men and women aged 55-75 years with overweight or obesity and metabolic syndrome. Using a validated, semiquantitative 143-item food frequency questionnaire completed at baseline, the dietary pattern adherence scores were calculated. An extensive neuropsychological test battery was administered at baseline and 2-year follow-up. Multivariable-adjusted linear regression models were used to assess associations between 2-year changes in cognitive function z-scores across tertiles of baseline adherence to the a priori dietary patterns. Results: Adherence to the Mediterranean diet at baseline was associated with 2-year changes in the general cognitive screening Mini-Mental State Examination (MMSE, β: 0.070; 95% CI: 0.014, 0.175, P-trend = 0.011), and two executive function-related assessments: the Trail Making Tests Part A (TMT-A, β: −0.054; 95% CI: −0.110, − 0.002, P-trend = 0.047) and Part B (TMT-B, β: −0.079; 95% CI: −0.134, −0.024, P-trend = 0.004). Adherence to the MIND diet was associated with the backward recall Digit Span Test assessment of working memory (DST-B, β: 0.058; 95% CI: 0.002, 0.114, P-trend = 0.045). However, higher adherence to the DASH dietary pattern was not associated with better cognitive function over a period of 2 years. Conclusion: In older Spanish individuals with overweight or obesity and at high cardiovascular disease risk, higher baseline adherence to the Mediterranean dietary pattern may be associated with better cognitive performance than lower adherence over a period of 2 years. Dieta Neurociència cognitiva Hàbits alimentaris Cognició Alimentació de les persones grans Diet Cognitive neuroscience Food habits Cognition Older people nutrition Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function: The 2-Year Longitudinal Changes in an Older Spanish Cohort