2026-04-19T15:54:57Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1838532025-12-04T19:03:34Zcom_2072_1057col_2072_478777col_2072_478917

00925njm 22002777a 4500 dc Gisbert Casas, Enric author Ibarz i Valls, Antoni author Firmino, Joana P. author Fernández-Alacid, Laura author Salomón, Ricardo author Vallejos Vidal, Eva author Ruiz, Alberto author Polo Pozo, Francisco Javier author Sanahuja Piera, Ignasi author Reyes López, Felipe E. author Tort Bardolet, Lluís author Andree, Karl B. author 2022-03-07T14:47:38Z 2022-03-07T14:47:38Z 2021-07-16 2022-03-07T14:47:38Z The effects of porcine plasma protein hydrolysate (PPH) on growth, feed efficiency, and immune responses was evaluated in Sparus aurata. Fish were fed two isoproteic (48% protein), isolipidic (17% fat), and isoenergetic diets (21.7 MJ/kg) diets, one of them containing 5% PPH at the expense of fishmeal. Both diets were tested for 92 days. A significant increase in growth was observed in fish fed the PPH diet in comparison to the control group (182.2 ± 4.4 vs. 173.8 ± 4.1 g), as well as an increase in feed intake without worsening FCR values. An ex vivo assay, with splenocytes incubated with lipopolysaccharide, was conducted to evaluate the cellular immune competence of fish. Genes involved in humoral immunity (lys, IgM), pro- (tnf-α, il-1β), and anti-inflammatory (tgf-β1, il10) cytokines were upregulated in the PPH group in comparison to the control group. The inclusion of PPH in diets enhanced the antibacterial capacity of skin mucus, as the co-culture of selected bacteria (E. coli, V. anguillarum, and P. anguilliseptica) with skin mucus indicated. The present results showed that the PPH in low fishmeal diets (2%) promoted growth and feed efficiency, as well as enhancing the immune response, which indicates that this is a safe and functional ingredient for aquafeeds. Aqüicultura Orada Nutrició animal Aquaculture Sparus aurata Animal nutrition Porcine Protein Hydrolysates (PEPTEIVA(r)) Promote Growth and Enhance Systemic Immunity in Gilthead Sea Bream (Sparus aurata)