2026-04-17T05:16:58Zhttps://recercat.cat/oai/request

oai:recercat.cat:2445/1799542025-12-05T13:14:39Zcom_2072_1057col_2072_478798col_2072_478858col_2072_478916col_2072_478917

00925njm 22002777a 4500 dc García Escobar, Eva author Valdés, Sergio author Soriguer, Federico author Vendrell, Joan author Urrutia Etxebarria, Inés María author Maldonado-araque, Cristina author Ortega Martínez de Victoria, Emilio author Ocón, Pilar author Montanya Mias, Eduard author Menendez, Eldelmiro author Lago Sampedro, Ana author González Frutos, Teba author Gomis, Ramon, 1946- author Goday Arnó, Albert author García Serrano, Sara author Galán García, José Luís author Castell, Conxa author Bordiú, Elena author Badía Guillén, Rocío author Aguilera Venegas, Gabriel author Girbés Borrás, Juan Adrián author Gaztambide, Sonia author Delgado Álvarez, Elías author Chaves, Felipe Javier author Castaño, Luis author Calle Pascual, Alfonso L. author Rojo Martínez, Gemma author Franch Nadal, Josep author 2021-09-10T10:39:43Z 2021-09-10T10:39:43Z 2021-08-12 2021-09-10T09:17:20Z Our aim was to evaluate whether fatty liver index (FLI) is associated with the risk of type 2 diabetes (T2DM) development within the Spanish adult population and according to their prediabetes status; additionally, to examine its incremental predictive value regarding traditional risk factors. A total of 2260 subjects (Prediabetes: 641 subjects, normoglycemia: 1619 subjects) from the Di@bet.es cohort study were studied. Socio-demographic, anthropometric, clinical data and survey on habits were recorded. An oral glucose tolerance test was performed and fasting determinations of glucose, lipids and insulin were made. FLI was calculated and classified into three categories: Low (< 30), intermediate (30-60) and high (> 60). In total, 143 people developed diabetes at follow-up. The presence of a high FLI category was in all cases a significant independent risk factor for the development of diabetes. The inclusion of FLI categories in prediction models based on different conventional T2DM risk factors significantly increase the prediction power of the models when all the population was considered. According to our results, FLI might be considered an early indicator of T2DM development even under normoglycemic condition. The data also suggest that FLI could provide additional information for the prediction of T2DM in models based on conventional risk factors. Diabetis Malalties del fetge Diabetes Liver diseases Fatty liver index as a predictor for type 2 diabetes in subjects with normoglycemia in a nationwide cohort study